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Respiratory Regulation - The Molecular Approach
This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders, cancer, respiratory allergies and cough, sleep disordered breathing and many others. Exciting new results and up-to-date critical overviews of widely debated topics pertaining to respiratory disorders are presented. The contributions provide evidence for the growing interest of the international community of researchers in the field of respiration. The book incorporates modern molecular approaches to diagnostic and treatment solutions, underscoring the need for rational, evidence-based treatment methods. Combining cutting edge basic and clinical research with expert knowledge and experience this book is essential reading for medical students, research scientists and practicing specialists in pulmonology, immunology and allergology.
Clinical Investigation
Clinical investigation plays an essential role in the differential diagnosis, biomarker development, and therapy and cure of diseases. The book presents a bench-to-bed approach, with broad empirical coverage by experienced practitioners. The articles include topics like cytokine receptors in lung cancer, conduciveness of oxidative stress to carcinogenesis, safety and effectiveness of surgical correction of deformed chest, diagnostic and treatment regimens in inflammation-ridden obstructive lung conditions, alterations in growth hormone secretion leading to disorders of growth and metabolism, microbiota transplantation in pediatric patients, and the promising markers of renal epithelial injury. Yet another issue concerns the restructuring of chronic pain management by establishing the community-based specialized pain clinics. The book aims to disseminate and deliberate on the latest interdisciplinary medical knowledge to enhance clinical outcomes. Being a blend of clinical investigation and practice the book is addressed to physicians, scientists, and allied health care professionals.
Neurotransmitter Interactions and Cognitive Function
A host of neurotransmitters and neuroactive substances underlies respiratory regulation in health and disease. The centerpiece of investigations regarding adaptation to hypoxia and sensorial perception has been the dopaminergic system. It is now clear that a complex interaction among various neuroactive substances, rather than a single one, forms the basis of respiratory changes. The research on neurotransmitter interactions provides the knowledge of how the brain functions and a new level of understanding of mind-to-body connection, which opens up avenues for novel therapeutic interventions.
Clinical Research Involving Pulmonary Disorders
This book presents the current trends and state of the art solutions addressing various issues related to pulmonary disorders. Diagnostic and therapeutic challenges are tackled, starting with the noncommunicable diseases of sarcoidosis and granulomatosis with polyangiitis. Pulmonary involvement, practically unavoidable, runs an insidious course, and is often occulted by systemic symptoms. The establishment of a firm diagnosis, with a precision no one could oppugn, is difficult. Other issues pertain to quality of life, disease preventive measures, and the move toward personal health care in chronic sufferers from multiple conditions in later life. There is also an update on the prevalence and diagnostic and treatment challenges of extrapulmonary tuberculosis. In addition, the place of neuroproteomics in modern clinical practice is presented. The practical insights emphasize the role of science in advancing biomedical knowledge and care. The book is addressed to researchers and practitioners, and allied health care professionals engaged in effective patient care and therapy.
Pulmonary Infection
The respiratory tract is a frequent target of infections caused by a wide range of organisms. The book provides reader-friendly information on aspects of pulmonary infections, including comprehensive accounts of bacterial and viral diseases, therapeutic approaches, molecular and classical culture-related techniques of diagnosis and explaining the basic cell biological mechanism. The role of oxidative stress, both helpful in fighting invading pathogens and detrimental in yielding to infection is detailed as it is often undervalued and needs focus. The chapters encompass latest developments and applications in bacteriology and virology, preventive and therapeutic tips, and raise attention to implementation of proper antibiotic policies by medical institutions to decrease resistance to antimicrobials. The perennial problem of low influenza vaccination coverage rate is rationalized. The volume will be of interest to both clinicians and biomedical researchers engaged in this exciting field.
Clinical Management of Pulmonary Disorders and Diseases
The book endeavors to provide a stimulating and thought provoking scientific content to share and exchange new clinical studies and advancements in dealing with pulmonary diseases. The topics vary from clinical to translational research in respiratory diseases such as lung cancer, obstructive sleep apnea, chronic obstructive pulmonary disease, bacterial and fungal infections, lung lesions during febrile maladies, and others. An attempt has been made to show the intertwined relationship between the pulmonary system and other body systems such as kidney, cardiac, or hormonal functions. The ensuing interlocked morbidities, often exacerbating one another, require the coordination of various medical specialties to optimize the diagnostic and therapeutic processes. The knowledge sharing through publications of research and clinical experiences is indispensable to accelerate the innovation spectrum and to continue working on the therapeutic and preventive strategies in chronic pulmonary diseases. The book is addressed to pulmonologists, chest physicians, researchers, and healthcare professionals engaged in patient care.
Neurobiology of Respiration
Respiration is an area of the medical study that undergoes fast developments. A better understanding of the neural and cellular mechanisms underlying respiratory disorders and lung function is essential for the evidence-based pharmacotherapy and for optimizing the patient care and prophylactic measures to improve the health and quality of life. This comprehensive book is a blend of basic and clinical research. The book is thought to promote the translation of science into clinical practice. The book presents an update on the areas of current research and clinical interest in the neurobiology of the respiratory system. Recent innovations in detection and management of respiratory diseases are described. The book will be a base of reference in the field of respiration for years to come and a source of future research ideas. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for ‘bench to bedside’ treatments of lung diseases.
Respiratory System Diseases
Both communicable and noncommunicable diseases of the respiratory system are an increasing healthcare problem despite medical advances. This book aims at unraveling the mechanisms and improving the treatment of pulmonary pathologies, ranging from such common conditions like influenza and related viral infections, functional lung dysfunction, to lung lesions and others. Chapters present late-breaking findings in the diagnostics, pharmacotherapy, and clinical evidence-based decision-making to provide results that can be used to improve healthcare and quality of life. Extending new knowledge and exploring recent medical advances, the book will hopefully help enrich research and clinical experience regarding important respiratory issues. The book is intended for general practitioners and all professionals engaged in the pulmonary field, from basic scientists to clinical investigators.
Neutrophil Extracellular Traps
Neutrophils regulate immune responses during homeostasis as well as disease pathogenesis. Especially, the neutrophils extracellular traps largely contribute to necroinflammation. This book highlights the role of neutrophils and neutrophils extracellular traps in various sterile and non-sterile, acute and chronic inflammatory conditions affecting both human and animal health.
Clinical Medicine Research
This book presents an update on new trends and developments in broadly defined medical disciplines. The whole range of multidisciplinary topics are tackled, regarded as being important for advancing the understanding of disease pathogenicity, diagnostic methods, and patient management. The topics include a holistic approach to physiotherapy, with proprioceptive neuromuscular facilitation at the core of it, potential ways to protect kidneys during ischemic coronary interventions, and psychosocial aspects in cancer survivors. Other topics deal with growth hormone deficiency in short children and responses of molecular markers of bone metabolism to growth hormone replacement therapy and with th...
