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Optimizing the "Drug-Like" Properties of Leads in Drug Discovery
This book arises from a workshop organized by the American Association of Pharmaceutical Scientists entitled "Optimizing the Drug-Like Properties of Leads in Drug Discovery," which took place in Parsippany, NJ in September 2004. The workshop focused on the optimization of the drug-like properties of leads in drug discovery. The volume outlines strategies and methodologies designed to guide pharmaceutical and biotechnology companies through the drug discovery and development process.
Secrets of Beaver Creek
Fiction that keeps you turning the page.
A History of the Italian Immigrants from the Seven Towns of the Asiago Plateau in the Region of the Veneto in Italy on the Gogebic Iron Range of Michigan and Wisconsin from the 1890s to the 1950s
For almost four decades, from 1890 to 1924, many European immigrants came to the Gogebic Iron Range of Michigan and Wisconsin to work in the iron mines, farm, and to establish businesses. Among them was a sizable group of Italian immigrants from various regions and provinces of Italy. This book is a history of a particular group of Italian immigrants that came from the Asiago Plateau in northern Italy. Their lives and experiences are given meaning in this book, bringing their families, friends and the general public, knowledge of their origins and background in northern Italy and the contributions they made on the Gogebic Iron Range. A thirty year research project, this book is a resource of information for families of the Asiago Plateau immigrants throughout the United States who wish to do historical or genealogical work. Furthermore, this book is a link with the people of the Asiago Plateau today and hopefully will be an aid for them to discover their
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Stability of Drugs and Dosage Forms
Drug products are complex mixtures of drugs and excipients and, as such, their chemical and physical stability kinetics are complex. This book discusses the stability of these dosage forms with preformulation studies through to the studies on the final products. The book is intended for graduate students, researchers and professionals in the field of Pharmaceutics and Pharmaceutical Chemistry.
Drug Discovery Handbook
The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. This comprehensive, practical guide presents an explanation of the latest techniques and methods in drug discovery, including: Genomics, proteomics, high-throughput screening, and systems biology Summaries of how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, and more Specific approaches to drug discovery, including problems that are encountered, solutions to these problems, and limitations of various methods and techniques The thorough coverage and practical, scientifically valid problem-solving approach of Drug Discovery Handbook will serve as an invaluable aid in the complex task of developing new drugs.
Prodrugs
These volumes represent a comprehensive guide to prodrugs. They guide the reader through the current status of the prodrug concept and its many applications and highlight its many successes in overcoming formulation and delivery of problematic drugs. Replete with examples of approved and marketed prodrugs, these volumes introduce the topic to the novice as well as professional in the design of prodrugs.
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Neoplastic Transformation in Human Cell Culture
The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi mental model systems. A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on April 25-26, 1991. The aims of the workshop were to present the state-of-the art in the transformation of human cells in culture, as well as to provide insight into the molecular and cellular changes involved in the conver sion of normal cells to a neoplastic state of growth. The following topics were closely related to the theme of the workshops: 1. Derivation of in v...
