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Systemic autoinflammatory diseases (SAIDs) are a growing group of rare disorders caused by dysregulation of the innate immune system leading to episodes of organ-specific and systemic inflammation. Autoinflammation as a distinct disease category was first reported in 1999 as a group of monogenic disorders with resultant activation of the inflammasome and cytokine excess, presenting as periodic fever and inflammation in serous membranes. Since this original description, the focus has shifted considerably to the inclusion of complex multifactorial conditions, and more than 30 associated genes have been identified. Disease severity varies from mild to life threatening. Advances in the understanding of the pathogenetic role of interleukin-1, have opened new promising horizons in the treatment of these patients, and significantly altered disease outcome.
Table of Contents: Piano per la formazione dei docenti 2016-2019, G. Domenici - Global Trends and Challenges for School Leaders, P. Earley - A Dispositional Approach to Examine the Impact towards Students Stressors in Indian Context, Chandrasekar Therasa and Chidambaram Vijayabanu - A Global Evaluation of Entrepreneurial Attitudes and Values, V. Caggiano, H. Akanazu, A. Furfari, A. Hageman - Valutazione per l'apprendimento vs. valutazione dell'apprendimento, C. La Rocca, R. Capobianco - Usare strumenti empirici per risolvere problemi, G. Asquini, F. Marano - Il metodo di studio come prima misura compensativa per l'inclusione degli allievi con DSA, L. Chiappetta Cajola, M. Traversetti - Poten...
Il presente lavoro raccoglie in due tomi i numerosi contributi presentati nell’ambito della Giornata della ricerca 2021, come nel quadro delle attività 2022, del Dipartimento di Scienze della Formazione dell’Università Roma Tre. I saggi contenuti nei due volumi rappresentano un’occasione di riflessione e di ricerca su temi, progetti, percorsi ed esiti, realizzazioni individuali o lavori di gruppo che si muovono in un arco tematico che va dai processi educativi e formativi - con l’analisi di dispositivi, la valutazione degli apprendimenti e delle competenze - fino a dimensioni ed ambiti storico-sociali; assumendo come linee di orientamento e sviluppo i concetti di inclusione, muta...
Moving, slowing down, or watching others moving allows people to cross physical, symbolic, and temporal boundaries. Exploring the imaginative power of liminality that makes this possible, Liminal Moves looks at the (im)mobilities of three groups of people - street monkey performers in Japan, adolescents writing about migrants in Italy, and men accompanying their partners in Switzerland for work. The book explores how, for these ‘travelers’, the interplay of mobility and immobility creates a ‘liminal hotspot’: a condition of suspension and ambivalence as they find themselves caught between places, meanings and times.