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Real-World Data and Real-World Evidence in Lung Cancer
Lung cancer is still one of the most common malignancies with a high global mortality rate with over 2 million cases confirmed by the World Health Organization in 2018. Although there has been progress in diagnosing and treating lung cancer, patients still have poor prognosis with a 5-year survival rate typically from 4-17% which is dependent on the stage of the cancer and regional differences. The majority of lung cancer patients are at the advanced stages of the disease at the time of their diagnosis and therefore, have less chances of early treatment that could have improved their survival rate. Therefore, early detection of lung cancer remains imperative to improve the prognosis.
Practical Medical Oncology Textbook
This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.
Ethics in Research
This book draws a connection between ethics and research across social sciences, philosophy, medical sciences and legal sciences, and demonstrates that any research activity needs to be conducted by means of rules deriving from the field of ethics. Although having a common core, such rules assume different characteristics depending on the branch of science, as the contributions on philosophy, medicine, dentistry, law, biotechnology, robotics and architecture highlight. It also investigates the more complex ethical concerns and places them in a larger, technological context. Starting with an introduction to common-sense ethical principles, the contributions then guide the reader, helping them develop and understand a comprehensive knowledge on the field. Notably, it appeared interesting to analyze recent events related to the arrival of the Sars-CoV-2 pandemic in light of ethical principles, highlighting in what terms their applicability can still be confirmed. Moreover, the book makes these topics accessible to a non-expert audience, while also offering alternative reading pathways to inspire more specialized readers.
Cardio-Oncology
The development of immunotherapy in oncology field has revolutionized the prognosis of many types of cancer. The immune checkpoint inhibitors target receptors whose inhibition increases the activity of immune system cells against tumor cells. In recent years, new immunotherapies have been studied and approved in a growing number of tumors including melanoma, non-small cell lung cancer (NSCLC), and renal cell cancer (RCC). This volume provides a complete and updated state-of-art review regarding the management of cardiovascular toxicities from new immunotherapies. The manuscript is divided into different sections starting from the relationship between cancer and immune system to let the reade...
