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The Structure And Function Of Ryanodine Receptors
This book provides up-to-date information on some of the most important aspects of ryanodine receptor function and has been written by experts in the field. Included are reviews of the latest experimental data, critical assessments of the mechanisms of ryanodine receptor activation and regulation, and the role of the channel in controlling intracellular Ca2+ release.The approach to this subject is new. The book focuses on the biochemical and biophysical aspects of ryanodine receptor research, with particular emphasis on the single channel properties of reconstituted ryanodine receptors.
Stress Response Pathways in Cancer
It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future. Coauthored by recognized leaders in cancer research from five continents, this novel book provides a comprehensive perspective on cell stress response pathways and therapeutic opportunities. Focusing on the role of genotoxic, proteotoxic, oxidative, metabolic, and inflammatory stress in tumorigenesis, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in cancer and therapeutic development.
International Review of Cytology
International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Phylogeny of the Insulin-Like Growth Factors Secretion of Mucous Granules and Other Membrane-Bound Structures Immune-Endocrine Interactions in the Mammalian Adrenal Gland Ryanodine-Sensitive Ca2+-Release Channels
Oligomerization in Health and Disease
This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Aaron Klug - A Long Way from Durban
The life and work of Aaron Klug, Nobel prize winner and one of the pioneers of structural molecular biology.
Using New Metabolic Approaches to Target and Eradicate Cancer Stem Cells
Topic Editors MPL and FS hold a minority interest in Lunella Biotech, Inc.
Membrane Dynamics and Calcium Signaling
This book describes the newest discoveries on calcium signaling happening at the cellular and intracellular membranes, often exerted in so called microdomains. Calcium entry and release, its interaction with proteins and resulting events on proteins and organelles are comprehensively depicted by leading experts in the field. Knowledge about details of these highly dynamic processes rapidly increased in recent years, the book therefore provides a timely summary on the processes of calcium signaling and related membrane dynamics; it is aimed at students and researchers in biochemistry and cell biology.
