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Dopamine
The chemical basis of human emotions has been an exciting aspect in biology. The "feel-good chemical" dopamine (DA) is a hormone and also a neurotransmitter, which performs a critical role in reward and movement control in the brain. DA also performs multiple other functions outside the brain. Regulating unrelated critical biological functions makes this chemical a vital factor for sustaining life in both health and disease. Dopamine - Health and Disease is an endeavour with an objective to understand and appreciate the biological functions of DA in human wellbeing and its potential utility in biomedical research. This effort will supplement scientific and non-scientific communities in stimulating a critical understanding of the biological purpose of "ticklish" DA, which eventually supports the human relentless effort to reduce the burden of disease. As the most exciting molecule,dopamine directly impacts day-to-day life. Anyone who has an eye for health and disease-related concepts will find this book a good read.
Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials
Despite being described about 200 years ago, the pathophysiology of Parkinson’s disease (PD) is not well understood due to its complex etiology and heterogeneity of symptoms and progression. Animal models provide a great opportunity to follow the progression of neurodegeneration and to screen potent therapeutic molecules, knowledge of which can be critical for different levels of clinical trials. Contemporary health technologies are coming in handy to accelerate the pace of developing novel and refined therapeutic strategies for PD. This book, Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials, provides a comprehensive overview of PD, presenting information on animal models of PD and contemporary therapeutic strategies, health technologies, clinical trials, and their influence on the quality of life of patients with PD.
Neural Synapse Research Trends
Chemical synapses are specialised junctions through which cells of the nervous system signal to one another and to non-neuronal cells such as muscles or glands. A chemical synapse between a motor neuron and a muscle cell is called a neuromuscular junction. Chemical synapses allow the neurons of the central nervous system to form interconnected neural circuits. They are thus crucial to the biological computations that underlie perception and thought. They also provide the means through which the nervous system connects to and controls the other systems of the body. The human brain contains a huge number of chemical synapses, with young children having about 1016 synapses (10,000 trillion[1].). This number declines with age, stabilising by adulthood. Estimates for an adult vary from 1015 to 5 × 1015 synapses (1,000 to 5,000 trillion).
The Last Town
The final book of the smash-hit Wayward Pines trilogy from the New York Times bestselling author of Dark Matter, Recursion, and Upgrade What’s inside was a nightmare. What’s outside is a thousand times worse. Welcome to Wayward Pines, the last town. Secret Service agent Ethan Burke arrived in Wayward Pines, Idaho, three weeks ago. In this town, people are told who to marry, where to live, where to work. No one is allowed to leave; even asking questions can get you killed. But Ethan has discovered the astonishing secret of what lies beyond the electrified fence that surrounds Wayward Pines and protects it from the terrifying world beyond. And now that secret is about to come storming through the fence to wipe out this last, fragile remnant of humanity. The Last Town at last pitches Ethan Burke and his fellow residents into all-out war against the forces outside the town’s gates – and in doing so delivers every bit the riotously horrific, breathlessly action-packed conclusion that the Wayward Pines trilogy deserves.
The Whereabouts of Eneas McNulty
Old God's Time (March 2023), Sebastian Barry's stunning new novel, available to pre-order now Following the end of the First World War, Eneas McNulty joins the British-led Royal Irish Constabulary. With all those around him becoming soldiers of a different kind, however, it proves to be the defining decision of his life when, having witnessed the murder of a fellow RIC policeman, he is wrongly accused of identifying the executioners. With a sentence of death passed over him he is forced to flee Sligo, his friends, family and beloved girl, Viv. What follows is the story of this flight, his subsequent wanderings, and the haunting pull of home that always afflicts him. Tender, witty, troubling and tragic, The Whereabouts of Eneas McNulty tells the secret history of a lost man.
Hearings
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The Valley
*Named one of Wall Street Journal's Best Books of 2015 *Selected as a Military Times's Best Book of the Year “You’re going up the Valley.” Black didn’t know its name, but he knew it lay deeper and higher than any other place Americans had ventured. You had to travel through a network of interlinked valleys, past all the other remote American outposts, just to get to its mouth. Everything about the place was myth and rumor, but one fact was clear: There were many valleys in the mountains of Afghanistan, and most were hard places where people died hard deaths. But there was only one Valley. It was the farthest, and the hardest, and the worst. When Black, a deskbound admin officer, is s...
Subtle Bodies
**A NEW YORK TIMES NOTABLE BOOK** In a sophisticated romp through the tribulations and joys of marriage and friendship, a group of college friends reunites two decades after graduation. After the sudden death of Douglas, once the ringleader of a clique of self-styled wits, his four best friends are summoned to his Catskills estate to mourn his passing. Responding to a mysterious sense of emergency in the call, Ned flies in from San Francisco with his wife Nina in furious pursuit; they’re at a critical point in their attempts to conceive and she won’t let a funeral get in the way. It is Nina who gives us a pointed, irreverent commentary as the men reconvene, while Ned tries to understand what it was that made this clutch of souls his friends to begin with—before time, sex, work, and the brutal quirks of history reshaped them. Filled with unexpected, funny, telling aperçus, Norman Rush’s Subtle Bodies is also a deeply moving exploration of the meanings of life.
