You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
The chemical basis of human emotions has been an exciting aspect in biology. The "feel-good chemical" dopamine (DA) is a hormone and also a neurotransmitter, which performs a critical role in reward and movement control in the brain. DA also performs multiple other functions outside the brain. Regulating unrelated critical biological functions makes this chemical a vital factor for sustaining life in both health and disease. Dopamine - Health and Disease is an endeavour with an objective to understand and appreciate the biological functions of DA in human wellbeing and its potential utility in biomedical research. This effort will supplement scientific and non-scientific communities in stimulating a critical understanding of the biological purpose of "ticklish" DA, which eventually supports the human relentless effort to reduce the burden of disease. As the most exciting molecule,dopamine directly impacts day-to-day life. Anyone who has an eye for health and disease-related concepts will find this book a good read.
Despite being described about 200 years ago, the pathophysiology of Parkinson’s disease (PD) is not well understood due to its complex etiology and heterogeneity of symptoms and progression. Animal models provide a great opportunity to follow the progression of neurodegeneration and to screen potent therapeutic molecules, knowledge of which can be critical for different levels of clinical trials. Contemporary health technologies are coming in handy to accelerate the pace of developing novel and refined therapeutic strategies for PD. This book, Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials, provides a comprehensive overview of PD, presenting information on animal models of PD and contemporary therapeutic strategies, health technologies, clinical trials, and their influence on the quality of life of patients with PD.
Chemical synapses are specialised junctions through which cells of the nervous system signal to one another and to non-neuronal cells such as muscles or glands. A chemical synapse between a motor neuron and a muscle cell is called a neuromuscular junction. Chemical synapses allow the neurons of the central nervous system to form interconnected neural circuits. They are thus crucial to the biological computations that underlie perception and thought. They also provide the means through which the nervous system connects to and controls the other systems of the body. The human brain contains a huge number of chemical synapses, with young children having about 1016 synapses (10,000 trillion[1].). This number declines with age, stabilising by adulthood. Estimates for an adult vary from 1015 to 5 × 1015 synapses (1,000 to 5,000 trillion).
Old God's Time (March 2023), Sebastian Barry's stunning new novel, available to pre-order now Following the end of the First World War, Eneas McNulty joins the British-led Royal Irish Constabulary. With all those around him becoming soldiers of a different kind, however, it proves to be the defining decision of his life when, having witnessed the murder of a fellow RIC policeman, he is wrongly accused of identifying the executioners. With a sentence of death passed over him he is forced to flee Sligo, his friends, family and beloved girl, Viv. What follows is the story of this flight, his subsequent wanderings, and the haunting pull of home that always afflicts him. Tender, witty, troubling and tragic, The Whereabouts of Eneas McNulty tells the secret history of a lost man.
To ten-year-old Suse Hansen, the fighting in Europe seems far away from the blue skies and quiet streets of her Bay Area home in Mendoza, California—despite newspaper war photographs and the tense radio broadcasts. But Pearl Harbor changes everything. Caught up in the fear and uncertainty of air raid drills, draft calls, and the mysterious departure of her Japanese and Italian neighbors, Suse becomes obsessed with the war. As Mendoza and the rest of America adjust to their new lives, Suse, too, will face challenges of her own as she begins to navigate the uncharted terrain of adolescence. Over the next four years she will confront the complexities of life—the demands of school, evolving friendships, brothers and sisters leaving home, the disturbing thrill of sexual awakening—while trying to understand who she is and what the future may hold for a world consumed by the horror of war. A rediscovered classic, Rumors of Peace is an extraordinary coming-of-age story chronicling the loss of American innocence through the voice of one remarkable young girl.
The final book of the smash-hit Wayward Pines trilogy from the New York Times bestselling author of Dark Matter, Recursion, and Upgrade What’s inside was a nightmare. What’s outside is a thousand times worse. Welcome to Wayward Pines, the last town. Secret Service agent Ethan Burke arrived in Wayward Pines, Idaho, three weeks ago. In this town, people are told who to marry, where to live, where to work. No one is allowed to leave; even asking questions can get you killed. But Ethan has discovered the astonishing secret of what lies beyond the electrified fence that surrounds Wayward Pines and protects it from the terrifying world beyond. And now that secret is about to come storming through the fence to wipe out this last, fragile remnant of humanity. The Last Town at last pitches Ethan Burke and his fellow residents into all-out war against the forces outside the town’s gates – and in doing so delivers every bit the riotously horrific, breathlessly action-packed conclusion that the Wayward Pines trilogy deserves.
None
'NDiaye is a hypnotic storyteller with an unflinching understanding of the rock-bottom reality of most people's life.' New York Times ' One of France's most exciting prose stylists.' The Guardian. Obsessed by her encounters with the mysterious green women, and haunted by the Garonne River, a nameless narrator seeks them out in La Roele, Paris, Marseille, and Ouagadougou. Each encounter reveals different aspects of the women; real or imagined, dead or alive, seductive or suicidal, driving the narrator deeper into her obsession, in this unsettling exploration of identity, memory and paranoia. Self Portrait in Green is the multi-prize winning, Marie NDiaye's brilliant subversion of the memoir. Written in diary entries, with lyrical prose and dreamlike imagery, we start with and return to the river, which mirrors the narrative by posing more questions than it answers.