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Albumin in Medicine
This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.
Acute Phase Proteins
The magnitude and rapidity of the changes in the concentrations of APPs, together with their short half-life, suggest an important role for these proteins in the establishment of host defense. APPs are regarded as having general functions in trapping of micro-organisms and their products, in activating complement, in binding cellular remnants like nuclear fractions, in neutralizing enzymes, scavenging free radicals, and in modulating the hosts immune response. Despite vast pro- and anti-inflammatory properties ascribed to individual APPs, their function during health and disease remains incompletely defined.
Nanobiotechnology
This book covers topics related to drug delivery, biomaterials, drug design, formulation development, nanoscience, and nanotechnology. It describes the fundamental concepts in nanotechnology and their different applications in biotechnology to solve engineering challenges and generate new areas of technological development. Nanobiotechnology: Applications of Nanomaterials in Biotechnology, Medicine, and Healthcare covers vast application areas that include medical science, material science, pharmaceutical science, and environmental science. Section 1 presents recent research updates on the different nanomaterials, which are promising in different medical and biotechnological applications. Ap...
Quantum Chemistry Simulation of Biological Molecules
This book covers quantum chemical simulation of molecular systems and their quantum chemical properties, alongside the most cutting-edge biomedical applications.
Micro- and Nanotechnologies-Based Product Development
This book provides comprehensive information of the nanotechnology-based pharmaceutical product development including a diverse range of arenas such as liposomes, nanoparticles, fullerenes, hydrogels, thermally responsive externally activated theranostics (TREAT), hydrogels, microspheres, micro- and nanoemulsions and carbon nanomaterials. It covers the micro- and nanotechnological aspects for pharmaceutical product development with the product development point of view and also covers the industrial aspects, novel technologies, stability studies, validation, safety and toxicity profiles, regulatory perspectives, scale-up technologies and fundamental concept in the development of products. Sa...
Human Serum Albumin (HSA)
Human Serum Albumin (HSA) is the most abundant plasma protein. It has been widely used for drug delivery systems and has recently emerged as a versatile carrier for therapeutic agents against diabetes, cancer and infectious diseases. This book provides an overview of the expanding field of preclinical and clinical applications and developments that use albumin as a carrier of drug delivery systems. The authors' discuss the properties of drug binding sites within the structure of HSA, discuss new possibilities for the therapeutic potential of HSA and analyze recently reported HSA-drug complexes including HSA-antibody conjugates. Novel investigations on the applications of albumin fusion proteins are discussed as well, with a focus on tumor targeting and intracellular delivery. Other chapters examine the different aspects of albumin glycation and oxidation, the changes in the structure of human serum albumin determined from infrared spectroscopy and a review of CAPIDAN, a special fluorescent dye, which attaches to drug binding sites of human serum albumin.
Nano Drug Delivery Strategies for the Treatment of Cancers
Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers...
The Thinsulin Program
High-fat, high-sugar foods get most of the blame for weight gain and obesity, but doctors have found that high insulin levels are actually the culprit. When we eat foods that raise our insulin level, the body stores fat; when we lower our insulin level, the body naturally burns fat. In The Thinsulin(TM) Program, bariatric internist Tu Song-Anh Nguyen and psychiatrist Charles Nguyen share their proven, science-based, two-stage plan for weight loss. First, the active phase shows you how to gain control of and lower your insulin levels through food choices that enable dramatic weight loss. Next, the passive phase helps you to adopt a new way of thinking about food, focusing on insulin rather than calories, to keep excess weight off for good.
Who's who Among Asian Americans, 1994-95
Provides biographical information, including career information and addresses, for notable Asian Americans in all fields of endeavour. The entries were selected on the basis of prominence in their fields or civic responsibility.
CPP, Cell-Penetrating Peptides
In this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of C...
