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Addressing the tuberculosis (TB) epidemic is crucial to reduce morbidity, mortality, and health-care burden. Cases of confirmed drug-resistant TB have almost doubled over the past decade. Drug resistance represents one of leading causes of death among TB patients and is responsible for approximately one-third of TB-related deaths worldwide, which is associated with TB recurrence and transmission. In recent years, the emerging molecular epidemiology methods have attributed to better TB management. For example, in many settings, studies using molecular epidemiology methods have demonstrated the recent transmission of Mycobacterium tuberculosis (M. TB) strains. However, the transmission pattern...
"Frontiers in Anti-Infective Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Infective drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and
Visually stunning and easy to use, this volume in the highly regarded Diagnostic Pathology series covers the normal histology of every organ system. This edition incorporates the most recent scientific and technological knowledge in the field to provide a comprehensive overview of all areas of normal histology, including introductory chapters on electron microscopy, immunofluorescence, immunohistochemistry and histochemistry, the cell, and the basic organization of tissues. With nearly 1,800 outstanding images, this reference is an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. Unparalleled visual coverage with carefully annotated photomicrographs, spectacul...
This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental condi...
Nanophytomedicine is a field that involves the application of nanomedicine-based systems to phytotherapy and phytopharmacology. This book assesses the clinical successes and failures of nanophytomedicine and also highlights emerging concepts in this field. The content is divided into three sections, the first of which describes core issues in the pharmaceuticals industry in connection with the successes, failures and prospects of nanophytomedicine. The second section highlights recent advances in phytomedicine formulation development based on nanotechnology approaches, while also discussing a variety of nanocarrier systems for the successful delivery of phytomedicines. Focusing on the clinic...