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This book is a compilation of some of the most remarkable contributions made by scientists currently working in Latin America to the understanding of virus biology, the pathogenesis of virus-related diseases, virus epidemiology, vaccine trials and antivirals development. In addition to recognizing the many fine virologists working in Latin America, Human Virology in Latin America also discusses both the state-of-the-art research and the current challenges that are being faced in the region, in hopes of inspiring young scientists worldwide to become eminent virologists.
This book is a printed edition of the Special Issue "Monoclonal Antibodies" that was published in Antibodies
Correlates of Protection (CoP) are biological parameters present in vaccinated or naturally infected individuals that predict levels of protection against an infectious disease. CoP facilitate vaccine licensing since they enable: a) the selection of antigen composition of a vaccine; b) the assessment of vaccine efficacy in clinical trials without exposure of participants to natural infection; and c) bridging between first- and second-generation vaccines.
This book highlights the estimate of epidemic characteristics for different countries/regions in the world with the use of known SIR (susceptible-infected-removed) model for the dynamics of the epidemic, the known exact solution of the linear differential equations and statistical approach developed before. The COVID-19 pandemic is of great interest to researchers due to its high mortality and a negative impact to the world economy. Correct simulation of the pandemic dynamics needs complicated mathematical models and many efforts for unknown parameters identification. The simple method of detection of the new pandemic wave is proposed and SIR model generalized. The hidden periods, epidemic durations, final numbers of cases, the effective reproduction numbers and probabilities of meeting an infected person are presented for countries like USA, Germany, UK, the Republic of Korea, Italy, Spain, France, the Republic of Moldova, Ukraine, and for the world. The presented information is useful to regulate the quarantine activities and to predict the medical and economic consequences of different/future pandemics.
An updated volume focusing on human virology and incorporating knowledge that has been gained in recent years, including contemporary information on the molecular biology of viruses.
World renowned scientists critically review the most important issues in this rapidly expanding field.
This book serves as a reference work on pediatric HIV infection and covers the full bandwidth of topics from an introduction to pathogenesis and epidemiology, over the transmission of the HI virus, to clinical manifestations, treatment, and prevention strategies. Diseases and disorders occurring in HIV infected persons are discussed in detail. The book covers special populations, such as neonates born to an HIV positive mother and adolescents and examines the specific ways of managing HIV disease in these patient groups. This is the first book to cover palliative care as well as ethical, legal and social issues of HIV infection.