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The Melanotropins
'This remarkable book ... Will be a kind of bible in which they can find practically all the facts, described in a critical and clear manner.' FEBS Letters.
Structure-based Ligand Design
Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design. Although this method first emerged in the 1980s, it has already become a powerful tool for pharmaceutical research. Much has been learned, however, since the first attempts to discover drugs on the basis of available biochemical and structural data. Nowadays, structure-based ligand design is an established method for creating drugs with new structural features, for modifying binding activities and pharmacokinetic properties, and for elucidating binding modes and structure-activity relationships. This vol...
The Making of Memory in the Middle Ages
Memory in the Middle Ages has received particular attention in recent decades; yet; the topic remains difficult to grasp and the research on it rather fragmented. This book gathers particular case studies on memory in different parts of medieval Europe and in a variety of fields including literatures, languages, manuscript studies, history, history of ideas, philosophy, social history and art history. The studies address, on the one hand, memory as means of storing and recuperating knowledge (arts of memory and memory aids), and, on the other hand, memory as remembering and constructing the past (including the subject of forgetting). It should be useful to all interested in medieval culture, literature and history. Contributors are Milena Bartlová, Bergsveinn Birgisson, Irene Bueno, Vincent Challet, Greti Dinkova-Bruun, Lucie Doležalová, Dávid Falvay, Carmen Florea, Cédric Giraud, Laura Iseppi de Filippis, Farkas Gábor Kiss, Rüdiger Lorenz, Else Mundal, Előd Nemerkényi, William J. Purkis, Slavica Ranković, Lucia Raspe, Kimberly Rivers, Victoria Smirnova, Francesco Stella, Péter Tóth, Tamás Visi, Jon Whitman and Rafał Wójcik.
Iron Curtain
'From Stettin in the Baltic to Trieste in the Adriatic an iron curtain has descended across the Continent. . .' With these words Winston Churchill famously warned the world in a now legendary speech given in Fulton, Missouri, on March 5, 1946. Launched as an evocative metaphor, the 'Iron Curtain' quickly became a brutal reality in the Cold War between Capitalist West and Communist East. Not surprisingly, for many years, people on both sides of the division have assumed that the story of the Iron Curtain began with Churchill's 1946 speech. In this fascinating investigation, Patrick Wright shows that this was decidedly not the case. Starting with its original use to describe an anti-fire devic...
Molecular Modeling
Written by experienced experts in molecular modeling, this books describes the basics to the extent that is necessary if one wants to be able to reliably judge the results from molecular modeling calculations. Its main objective is the description of the various pitfalls to be avoided. Without unnecessary overhead it leads the reader from simple calculations on small molecules to the modeling of proteins and other relevant biomolecules. A textbook for beginners as well as an invaluable reference for all those dealing with molecular modeling in their daily work!
Neurohypophysis
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Understanding Graffiti
This collection of original articles brings together for the first time the research on graffiti from a wide range of geographical and chronological contexts, and shows how they are interpreted in fields as diverse as archaeology, art history, museum studies, and sociology.
The Design of Material, Organism, and Minds
Design is eminent throughout different disciplines of science, engineering, humanities, and art. However, within these disciplines, the way in which the term design is understood and applied differs significantly. There still is a profound lack of interdisciplinary research on this issue. The same term is not even guaranteed to carry the same meaning as soon as one crosses over to other disciplines. Therefore, related synergies between disciplines remain largely unexplored and unexploited.This book will address design in the hope of promoting a deeper understanding of it across various disciplines, and to support Design Science as a discipline, which attempts to cover the vast number of currently isolated knowledge sources.
Nuclear Physics Methods and Accelerators in Biology and Medicine
These proceedings are a collection of manuscripts of the lectures given at the Fourth International Summer School on Nuclear Physics Methods and Accelerators in Biology and Medicine. They provide a broad up-to-date review of the current knowledge and methods of Nuclear Physics and Particle Accelerators and their applications in medicine and biology. The material here will be of huge interest to university students of engineering, physics, medicine, and biology.
