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Wh-movement and the theory of feature-checking argues that cross-linguistic variation in wh-constructions reduces to the availability of different lexical instantiations of a +wh C0 both across languages and within a single language, and the way in which such lexical elements are syntactically identified, either via movement or base-generation. Evidence from a wide range of patterns including wh-expletive questions leads to the conclusion that wh-feature checking may sometimes be effected non-locally and 'at a distance' (long-distance wh-agreement), and that movement in general takes place for two related but discrete reasons: both to identify and activate an underspecified licensing head and in order for an element to occur in the checking domain projected by its relevant licensing head. Developing and generalizing the proposals beyond wh-phenomena, the study also goes on to argue for a Minimalist model of syntax in which feature-dependencies are in fact all licensed in the overt syntax and where there is no need for any further level of LF.
This book brings together perspectives on predictive processing and expected experience. It features contributions from an interdisciplinary group of authors specializing in philosophy, psychology, cognitive science, and neuroscience. Predictive processing, or predictive coding, is the theory that the brain constantly minimizes the error of its predictions based on the sensory input it receives from the world. This process of prediction error minimization has numerous implications for different forms of conscious and perceptual experience. The chapters in this volume explore these implications and various phenomena related to them. The contributors tackle issues related to precision estimation, sensory prediction, probabilistic perception, and attention, as well as the role predictive processing plays in emotion, action, psychotic experience, anosognosia, and gut complex. Expected Experiences will be of interest to scholars and advanced students in philosophy, psychology, and cognitive science working on issues related to predictive processing and coding.
Early embryo development in mammals begins with the recognition and fusion of gametes of both sexes, followed by a series of mitotic cell divisions. The gamete fusion results in the formation of totipotent cells, which are capable of developing into three basic cell lineages in mammals. These include the trophoblast, surrounding the embryo and facilitating communication with the mother, the epiblast which develops into the fetus, and the primitive endoderm which forms the yolk sac. Until implantation, the embryos undergo remarkable changes, including histone modifications, chromatin remodeling, epigenetic modifications of chromatin, the onset of transcription from the embryonic genome, and the first differentiation to the formation of the trilaminar disc, containing all primary cell lineages required for the formation of fetal tissues and organs. Remarkably, some of the most complex events of early development, such as fertilization, are achieved during complete transcriptional silencing. Another unique feature is how fast the development proceeds. In humans, reaching the stage of early gastrulation takes approximately two weeks.
"This book is a comprehensive and in-depth reference to the most recent developments in the field covering theoretical developments, techniques, technologies, among others"--Provided by publisher.
This third volume in the successful 'Drug Discovery in Infectious Diseases' series is the first to deal with drug discovery in helminthic infections in human and animals. The result is a broad overview of different drug target evaluation methods, including specific examples of successful drug development against helminthes, and with a whole section devoted to vaccine development. With its well-balanced mix of high-profile contributors from academia and industry, this handbook and reference will appeal to a wide audience, including parasitologists, pharmaceutical industry, epidemiologists, and veterinary scientists.
The contributors to this book have spent time and effort presenting the cosmetic and plastic surgeon with information on the techniques and uses of liposuction for cosmetic and non-cosmetic surgery purposes. This constitutes the first book on cosmetic and non-cosmetic liposuction. It provides a how-to-do manual for all procedures of cosmetic and non-cosmetic liposuction and is abundantly illustrated. Although new technology helps improve results, it is experience, care, and skill of the cosmetic surgeon that is necessary to obtain optimal results that satisfy the patient.