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Mechanisms, Transmissions and Applications
  • Language: en
  • Pages: 290

Mechanisms, Transmissions and Applications

  • Type: Book
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  • Published: 2017-06-09
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  • Publisher: Springer

This volume contains the proceedings of MeTrApp 2017, the 4th Conference on Mechanisms, Transmissions and Applications, that was held in Trabzon, Turkey, July 3-5, 2017. The topics treated in this volume are Mechanism Design, Parallel Manipulators, Control Applications, Mechanical Transmissions, Cam Mechanisms, and Dynamics of Machinery. The conference was organised by the IFToMM Technical Committees for “Linkages and Mechanical Controls” and “Gearing and Transmissions” under the patronage of the IFToMM and sponsorship of Karadeniz Technical University, Izmir Institute of Technology and IFToMM Turkey (MAKTED). The aim of the conference was to bring together researchers, scientists, industry experts and students to provide, in a friendly and stimulating environment, the opportunity to exchange know-how and promote collaboration in the field of Mechanism and Machine Science.

Serotonin
  • Language: en
  • Pages: 318

Serotonin

Serotonin - A Chemical Messenger Between All Types of Living Cells is a very interesting book on the most ancient neurotransmitter, hormone and trophic factor serotonin or 5-hydroxytryptamine (5-HT). This unique chemical is present in all living cells including plants and animals. This book will take us through a serene journey of the evolutionary history of serotonin and its role from man to mollusk. There are many interesting chapters incorporated in this book, including novel approaches for detecting minor metabolites of serotonin in human plasma, production and function of serotonin in cardiac cells, immuno-thrombotic effects of serotonin in platelets to the identification and localization of serotonin in the nervous system and gonad of bivalve mollusks.

Advances in Mechanism and Machine Science
  • Language: en
  • Pages: 4203

Advances in Mechanism and Machine Science

  • Type: Book
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  • Published: 2019-06-13
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  • Publisher: Springer

This book gathers the proceedings of the 15th IFToMM World Congress, which was held in Krakow, Poland, from June 30 to July 4, 2019. Having been organized every four years since 1965, the Congress represents the world’s largest scientific event on mechanism and machine science (MMS). The contributions cover an extremely diverse range of topics, including biomechanical engineering, computational kinematics, design methodologies, dynamics of machinery, multibody dynamics, gearing and transmissions, history of MMS, linkage and mechanical controls, robotics and mechatronics, micro-mechanisms, reliability of machines and mechanisms, rotor dynamics, standardization of terminology, sustainable energy systems, transportation machinery, tribology and vibration. Selected by means of a rigorous international peer-review process, they highlight numerous exciting advances and ideas that will spur novel research directions and foster new multidisciplinary collaborations.

Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation
  • Language: en
  • Pages: 467

Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation

This concise, accessible book covers anesthesia for hepatico-pancreatic-biliary (HPB) surgery and transplantation, based on randomized clinical trials, meta-analyses, case series, reports, and hands-on experience. The anatomy, physiology, pathophysiology and clinical consequences are discussed, and the close ties between HPB resection and transplant anesthesia are explored. The content reflects current real-world practice, as liver and pancreatic transplant surgeries have substantially improved in terms of blood-loss reduction, fast tracking and reduced risk. The book also addresses anesthetic aspects in connection with the recently introduced and rapidly expanding practice of laparoscopic surgery; with enhanced recovery; and with pancreatic surgery. Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation is intended for aspiring HPB and transplant anesthetists, anesthesia trainees, and consultants with experience in HPB anesthesia who want to see whether or not they’re up to date on the current standards.

Privileged Structures in Drug Discovery
  • Language: en
  • Pages: 560

Privileged Structures in Drug Discovery

A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book...

Voltage-Gated Ion Channels as Drug Targets
  • Language: en
  • Pages: 492

Voltage-Gated Ion Channels as Drug Targets

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.

Progress in Drug Research
  • Language: en
  • Pages: 371
Advances in Service and Industrial Robotics
  • Language: en
  • Pages: 755

Advances in Service and Industrial Robotics

  • Type: Book
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  • Published: 2018-09-28
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  • Publisher: Springer

This volume contains the proceedings of the RAAD 2018 conference, covering major areas of research and development in robotics. It provides an overview on the advances in robotics, more specifically in novel design and applications of robotic systems; dexterous grasping, handling and intelligent manipulation; intelligent cooperating and service robots; advanced robot control; human-robot interfaces; robot vision systems and visual serving techniques; mobile robots; humanoid and walking robots; field and agricultural robotics; bio-inspired and swarm robotic systems; developments towards micro and nano-scale robots; aerial, underwater and spatial robots; robot integration in holonic manufacturing; personal robots for ambient assisted living; medical robots and bionic prostheses; intelligent information technologies for cognitive robots etc. The primary audience of the work are researchers as well as engineers in robotics and mechatronics.

Concepts and Principles of Pharmacology
  • Language: en
  • Pages: 457

Concepts and Principles of Pharmacology

Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Trends in Receptor Research
  • Language: en
  • Pages: 445

Trends in Receptor Research

  • Type: Book
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  • Published: 2013-10-22
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  • Publisher: Elsevier

The 8th Camerino-Noordwijkerhout Symposium has continued along its traditional path of interdisciplinary cooperation. Chemists, biochemists, pharmacologists, biophysicists and physiologists are all involved in the task of improving our knowledge of the mechanisms of drug-receptor interaction and of the heterogeneous nature of biological molecules. In this volume, leading researchers have contributed state of the art information on receptor chemistry. Newest developments are covered with particular reference to receptors of the nervous system; SAR studies; receptor isolation; receptor cloning; receptor topography; biomedical consequences of occupancy; receptor regulation and receptor theory. This will be of great interest to pharmacologists, biochemists and medicinal chemists, as well as a valuable source of reference for medical students and postgraduate students in related fields.