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Regulation of Angiogenesis
We now know that excessive angiogenesis contributes to the development of a variety of disease processes, including cancer, chronic inflammatory disease, and diabetic retinopathy. On the other hand, insufficient angiogenesis may impair wound healing and organ repair. This volume describes recent advances in understanding the molecular regulation of angiogenesis. Subjects covered include important pro-angiogenic growth factors (e.g., vascular endothelial growth factor/vascular permeability factor, scatter factor/hepatocyte growth factor) and their receptors; angiogenesis inhibitors (e.g., thrombospondin-1, angiostatin); extracellular matrix factors (e.g., laminin) and specific vascular integr...
NASA Technical Note
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Tales of Imperial Russia
History and biography meet in Tales of Imperial Russia, a study of the late-Romanov Russian Empire, told through the figure of Sergei Witte. Like Bismarck or Gorbachev, Witte was a European statesman serving an empire. He was the most important statesman of pre-revolutionary Russia. In the Georgia, Odessa, Kyiv, and St. Petersburg of the nineteenth century, he inhabited the worlds of the Victorian Age, as young boy, student, railway executive, lover of divorcees and Jews, monarchist, and technocrat. His political career saw him construct the Tran-Siberian Railway, propel Russia towards Far Eastern war with Japan, visit America in 1905 to negotiate the Treaty of Portsmouth concluding that war...
NASA Technical Paper
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