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Biomimetic Organic Synthesis
In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of complex natural products is laid out, backed by abundant practical examples from the authors' own work as well as from the published literature. Volume 1 describes the biomimetic synthesis of alkaloids. Volume 2 covers terpenes, polyketides, and polyphenols. A discussion of the current challenges and frontiers in biomimetic synthesis concludes this comprehensive handbook. Key features: Biomimetic Strategies have become an every-day tool not only for chemists but also for biologists. The synthetic applications are overwhelming, making this comprehensive 2 volume work a must-have for everyone working in the field. Unifying both synthetic and biosynthetic aspects, this book covers everything from organocatalysis and natural product synthesis to synthetic biology and even green chemistry.
Drug Discovery from Natural Products
An integrated review of the most recent trends in natural products, drug discovery, and key lead candidates that are outstanding for their chemistry and biology in novel drug development.
The Hidden Life of Trees: What They Feel, How They Communicate
Sunday Times Bestseller‘A paradigm-smashing chronicle of joyous entanglement’ Charles Foster Waterstones Non-Fiction Book of the Month (September) Are trees social beings? How do trees live? Do they feel pain or have awareness of their surroundings?
Cyclic Peptides
This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.
The Heartbeat of Trees
This book marks a powerful return to the forest, where trees have heartbeats and roots are like brains that extend underground, where the colour green calms us and the forest sharpens our senses. In The Heartbeat of Trees, renowned forester Peter Wohlleben draws on new scientific discoveries to show how humans are deeply connected to the natural world. In an era of cell-phone addiction, climate change and urban life, many of us fear that we've lost our connection to nature. But Wohlleben is convinced that the age-old ties linking humans to the forest remain alive and intact. Drawing on science and cutting-edge research, The Heartbeat of Trees reveals the profound interactions humans can have...
Ultrafast Phenomena XIV
Ultrafast Phenomena XIV presents the latest advances in ultrafast science, including ultrafast laser and measurement technology as well as studies of ultrafast phenomena. Pico-, femto-, and atosecond processes relevant in physics, chemistry, biology and engineering are presented. Ultrafast technology is now having a profound impact within a wide range of applications, among them imaging, material diagnostics, and transformation and high-speed optoelectronics. This book summarizes results presented at the 14th Ultrafast Phenomena Conference and reviews the state of the art in this important and rapidly advancing field.
Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides
Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject wi...
The Bacteriophages
This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity.Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.
Nitrogen Fixation
This volume constitutes the proceedings of an international meeting held from June 28 to July 1, 1981, at Zif, Zentrum far Interdisziplin~re Forschung an der Universit~t Bielefeld, West Germany. The meeting was one of a continuing series organized through Zif on topics which transcend the boundaries of the traditional academic disciplines. The almost exponentially growing area of nitrogen fixation research fits this criterion completely. It is, however, so broad that we oriented and focused the meeting on just the chemical, biochemical, and genetic aspects to maximize the interaction among the participants and to produce a volume which would serve as a reference source for the involved researcher, the newly interested scientist and those with a more casual interest. The meeting was generously supported by Zif, the Westf~lisch Lippische Universit~tsgesellschaft, and the Fonds der Chemischen Industrie. We sincerely thank these organizations for their generosity and interest and for recognizing the importance of nitrogen fixation research for the future of mankind.
Emerging Frontiers in Nonlinear Science
This book explores the impact of nonlinearity on a broad range of areas, including time-honored fields such as biology, geometry, and topology, but also modern ones such as quantum mechanics, networks, metamaterials and artificial intelligence. The concept of nonlinearity is a universal feature in mathematics, physics, chemistry and biology, and is used to characterize systems whose behavior does not amount to a superposition of simple building blocks, but rather features complex and often chaotic patterns and phenomena. Each chapter of the book features a synopsis that not only recaps the recent progress in each field but also charts the challenges that lie ahead. This interdisciplinary book presents contributions from a diverse group of experts from various fields to provide an overview of each field’s past, present and future. It will appeal to both beginners and seasoned researchers in nonlinear science, numerous areas of physics (optics, quantum physics, biophysics), and applied mathematics (ODEs, PDEs, dynamical systems, machine learning) as well as engineering.
