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Current Perspectives in microRNAs (miRNA)
Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native miRNA species fo...
Waṣf Ṣanʻā
This work is the first book-length ethno-linguistic study of Sanan?- Arabic. The book comprises twenty-eight original oral texts which have been transcribed, translated and annotated by the author, a linguistic introduction to the texts, a glossary of all words contained in the texts, and a list of references. Each of the texts deals with one or more aspects of Yemeni culture. These include: the old city, oil presses, the old watercourse, bread, the development of restaurants, Yemeni cooking and recipes, travel in Yemen, gat, Yemeni architecture, the water-pipe, children's games of yesterday and today, Islamic festivals, and weddings. The texts are principally descriptions, narratives or mixed descriptive-narratives of personal experience. Together they tell a story of change and of what remains despite the forces of change - the rules of hospitality, fasting, food, the bath-houses - and show Yemen as a country where tradition and innovation are intriguingly interwoven.
The Brassicaceae — Agri-Horticultural and Environmental Perspectives
This Frontiers Research Topic "The Brassicaceae- Agri-Horticultural and Environmental Perspectives" is an effort to provide a common platform to agronomists, horticulturists, plant breeders, plant geneticists/molecular biologists, plant physiologists and environmental plant scientists exploring major insights into the role of important members of the plant family Brassicaceae (the mustard family, or Cruciferae) in agri-horticultural and environmental arenas.
MicroRNA Expression Detection Methods
MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of - nucleotides, have rapidly emerged as the central players in gene expression regulation. Owing to their ever-increasing implications in the control of various biological and pathological processes, miRNAs have now been considered novel biomarkers of various human diseases including, cancer, viral disease, cardiov- cular disorders, metabolic disturbances, etc. Particular expression pro?les have been associated with particular pathological states. Expression pro?ling of miR- NAs have therefore become extremely important not only for fundamentalists but also for clinicians. However, the methodologies used for detecting protein-coding...
MicroRNAs in Cancer Translational Research
MicroRNA (miRNA) is a cutting-edge topic in the scientific and medical fields. This is a timely and specialized book focusing on the current understanding of miRNAs and the potential for their application in cancer diagnosis, prognosis, and therapeutic targets. It also provides discussion of the lessons learned from translational miRNA studies and exploration of the next steps required to advance this field. The unique book comprises 22 in-depth chapters by gathering unparalleled topics of interest in miRNAs by international team of world-renowned experts in the field. The first fifteen chapters provide comprehensive and expert perspectives on the most common cancers from bench to bedside ap...
Pharmaceutical Perspectives of Cancer Therapeutics
Pharmaceutical Perspectives of Cancer Therapeutics covers a wide variety of therapeutic approaches including gene therapy, immunological therapy; cancer vaccines; strategy for solid tumors as well as for hematological cancers; methods to suppress tumor angiogenesis and metastasis; development and utilization of relevant animal models; introduction of new concepts such as cancer stem cells and new technologies, such as DNA and tissue microarrays; and RNA interference. In addition, clinical application, the development of DNA diagnosis biomarkers and cancer prevention, as well as the utilization of imaging in cancer therapy are also discussed. The use of synthetic carriers, such as lipids, polymers, and peptides for delivery and targeting of small molecules, proteins, and nucleic acids to cancer cells in vivo are discussed. Pharmaceutical Perspectives of Cancer Therapeutics also includes cancer therapy modality in surgery, chemotherapy, and radiotherapy, as well as in combination or multi-modality, giving our book a more focused view of cancer therapy.
Ovarian Cancer: New Insights for the Healthcare Professional: 2012 Edition
Ovarian Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Ovarian Cancer. The editors have built Ovarian Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ovarian Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Ovarian Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
No Word for Welcome
Wendy Call visited the Isthmus of Tehuantepec—the lush sliver of land connecting the Yucatan Peninsula to the rest of Mexico—for the first time in 1997. She found herself in the midst of a storied land, a place Mexicans call their country's "little waist," a place long known for its strong women, spirited marketplaces, and deep sense of independence. She also landed in the middle of a ferocious battle over plans to industrialize the region, where most people still fish, farm, and work in the forests. In the decade that followed her first visit, Call witnessed farmland being paved for new highways, oil spilling into rivers, and forests burning down. Through it all, local people fought to protect their lands and their livelihoods—and their very lives. Call's story, No Word for Welcome, invites readers into the homes, classrooms, storefronts, and fishing boats of the isthmus, as well as the mahogany-paneled high-rise offices of those striving to control the region. With timely and invaluable insights into the development battle, Call shows that the people who have suffered most from economic globalization have some of the clearest ideas about how we can all survive it.
Toxicology and Epigenetics
Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in r...
DNA Nanotechnology for Cell Research
DNA Nanotechnology for Cell Research Comprehensive coverage of DNA nanotechnology with a focus on its biomedical applications in disease diagnosis, gene therapy, and drug delivery Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DN...
