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For the past decade or more, much of cell biology research has been focused on determining the key molecules involved in different cellular processes, an analytical problem that has been amenable to biochemical and genetic approaches. Now, we face an integrative problem of understanding how all of these molecules work together to produce living cells, a challenge that requires using quantitative approaches to model the complex interactions within a cell, and testing those models with careful quantitative measurements. This book is an introductory overview of the various approaches, methods, techniques, and models employed in quantitative cell biology, which are reviewed in greater detail in the other volumes in this e-book series. Particular emphasis is placed on the goals and purpose of quantitative analysis and modeling, and the special challenges that cell biology holds for understanding life at the physical level.
Wallace is the classic portrait of one of the century's most fiery and controversial political figures. Initially conceived as a novel, Marshall Frady's biography retains the narrative force and descriptive powers of fiction. This is a depiction of George Wallace, a seminal figure of the second half of the twentieth century whose influence has altered the course of national politics.
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This book focuses on the interaction between practising economists and previous generations of economists. Because economic problems, such as crashes, tend to recur and are only partially understood, it may be profitable read the work of previous generations in a collaborative spirit. Sometimes this can offer a different perspective on current preoccupations and cause us to reconsider the scope of our much criticised subject. The book gathers together earlier work by the author which appeared in various academic books and journals with the addition of six new chapters. The collection makes for a lively, informative and thought-provoking collection. It will interest anyone with an interest in the history of economics and of economic thought.
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers cilia Contains chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins
In the presidential campaign of 1948, Henry Wallace set out to challenge the conventional wisdom of his time, blaming the United States, instead of the Soviet Union, for the Cold War, denouncing the popular Marshall Plan, and calling for an end to segregation. In addition, he argued that domestic fascism--rather than international communism--posed the primary threat to the nation. He even welcomed Communists into his campaign, admiring their commitment to peace. Focusing on what Wallace himself later considered his campaign's most important aspect, the troubled relationship between non-Communist progressives like himself and members of the American Communist Party, Thomas W. Devine demonstra...
pt. 1. List of patentees.--pt. 2. Index to subjects of inventions.