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Channels, Carriers, and Pumps
An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. - Provides an introduction to the properties of transport proteins: channels, carriers, and pumps - Presents up-to-date information on the structure of transport proteins and on their function and regulation - Includes introductions to transport kinetics and to the cloning of genes that code transport proteins - Furnishes a link between the experimental basis of the subject and theoretical model building
Transport And Diffusion Across Cell Membranes
Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane ...
International Review of Cytology
International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Cell Membrane Transport
Experimental science is a complicated creature. At the head there is a Gordian knot of ideas and hypotheses; behind is the accumulated mass of decades of research. Only the laboratory methods, the legs which propel science forward, remain firmly in touch with the ground. Growth, however is uneven; dinosaurs develop by solid means to give a vast body of results, but few ideas. Others sprint briefly to success with brilliant, though ill-supported, ideas. The problems which this book addresses is to maintain an organic unity between new ideas and the current profusion of innovative experimental tools. Only then can we have the framework on which our research thoughts may flourish. The contribut...
Moving Questions
This book describes a half century of research on cellular membrane transport and on metabolic energy capture and utilization. During this time-which begins in the late 1930s-the effort and imagination of various scientists overthrew reigning formulations, created novel explanatory models, and unified previously distinct experimental fields. My primary goal is to display the course of that research, showing how new experiments defined novel entities and processes, and how an encompassing field, bioenergetics, then emerged. A secondary goal is to present examples of mainstream biological research that illustrate how experimental results-seen as refutations, confirmations, and elabora tions-ca...
International Review of Cytology V146
International Review of Cytology V146
Biosciences 2000: Current Aspects And Prospects Into The Next Millenium
As the new millennium approaches, it is appropriate to ask how far medicine and the life sciences have brought us, and to wonder how specific fields will develop over the next decade or so.This volume gathers together a number of leading scientists to give a bird's eye view of their field. Much of the emphasis is on cancer, microbial infections and immunology, because these are some of the most rapidly advancing areas of research. However, the book is wide-ranging and interdisciplinary, and covers topics as diverse as reproductive health technology, animal-to-human transplants, drug resistance, non-invasive diagnosis by magnetic resonance, novel membrane technology, and carbon nanotubes. The graduate student faced with a decision regarding his or her future topic of research could do worse than browse through this collection of articles by experts in the field.
Corporeal Cartographies
The book focuses on the importance of corporeality in Leonard Cohen's prose works The Favourite Game (1963) and Beautiful Losers (1966). It argues that prevailing post-structuralist theories that describe the body as discursively constructed cannot do justice to the real and violent proportions of the bodies in Cohen's visionary texts. These theories should be complemented by the neo-materialist approach developed by French philosophers Gilles Deleuze and FÃ?Â(c)lix Guattari, who stress the importance of physical forces and intensities that affect the production and the expression of bodies, both in life and art. (Series: n-1 / work - science - medium - Vol. 4)
