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This new book uniquely integrates the diversity of research and interest regarding the chemistry, analysis, physiology, genetics, and clinical aspects of vitamin K and vitamin K-dependent proteins. Featuring state-of-the-art reviews of analytical methods used in various fields of study relating to vitamin K this book demonstrates how methodological advances are advancing our knowledge in these fields. Topics covered include the hemostatic function; congenital deficiencies and role in malignancy of vitamin K-dependent procoagulants and anticoagulants; etiology, diagnosis, and prevention of vitamin K deficiency in the newborn; and biochemical perspectives of vitamin K deficiency or antagonism induced by antibiotics or coumarin drugs. Vitamin K and Vitamin K-Dependent Proteins also discusses the physiology and diagnostic role of the bone-protein osteocalcin and other non-coagulation vitamin K-dependent proteins. The book is an indispensable reference for hematologists, biochemists, physiologists, and nutrition researchers.
Reprint of the original, first published in 1883.
First multi-year cumulation covers six years: 1965-70.
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