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Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.
The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SP
Because stroke is essentially a disease of the vessels and blood flow, the most fundamental aspects of ischemic blood flow in the brain are under investigation by researchers. Their work was the focus of the sixth in the series of Keio University International Symposia for Life Sciences and Medicine, held in Tokyo in 1999. Selected here are 55 papers from the symposium, covering the buffy coat (glycocalyx) of endothelial cells, the blood-brain barrier and permeability, gene expression, vascular reactivity, dysregulation, inflammatory deterioration, cortical spreading depression, edema, microvascular derangement, and pathology, in ten major sections. The book includes the thought-provoking discussions that followed the presentations, thus providing an invaluable source of up-to-date information not only for researchers investigating microcirculation but also for clinicians implementing the most effective treatment for stroke patients.
This book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, β-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. A wide range of systems not addressed in the first edition are covered, reflecting the advances made in recent years. The book combines the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all with an interest in clinical and preclinical neuroscience. Companion volumes on the use of PET and SPECT in neurology and psychiatry complete a trilogy.
This book traces the various configurations of food as hunger, desire, and appetite which point to the complex dialectic of consumption and consummation of ideas and forms underpinning the arts. It examines the relationship between nature and science, space and the act of artistic creation, desire and the arts, appetite and hunger. One of the aims of the book is to explore established theoretical and historical conceptions of “nature” in the arts and re-think their relationship to appetite in the globalized world. Examining the many guises and figurations of hunger in literature and the arts, this book gives an overview of the themes that emerge from the idea of the Hunger Artist alongsi...
This book, now in its revised and updated third edition, provides a state of the art overview of fMRI and its use in clinical practice. Experts in the field share their knowledge and explain how to overcome diverse potential technical barriers and problems. Starting from the very basics on the origin of the BOLD signal, the book covers technical issues, anatomical landmarks, methods of statistical analysis, and special issues in various clinical fields. Comparisons are made with other brain mapping techniques and their combined use with fMRI is also discussed. Existing chapters have been updated and new chapters have been added in order to account for new applications, further clinical fields and methods, e.g. resting state fMRI. Based on the clinical focus, this book will be of great value for Neuroradiologists, Neurologists, Neurosurgeons but also Researchers in Neuroscience.
This book tells the full story of stroke through the experiences of many who were 'eye' witnesses to this long process.
The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SP
One of Victorian England’s most famous philosophers harbored a secret: Herbert Spencer suffered from an illness so laden with stigma that he feared its revelation would ruin him. He therefore went to extraordinary lengths to hide his malady from the public. Exceptionally, he drew two of his closest friends—the novelist George Eliot and her partner, G. H. Lewes—into his secret. Years later, he also shared it with a remarkable neurologist, John Hughlings-Jackson, better placed than anyone else in England to understand his illness. Spencer insisted that all three support him without betraying his condition to others—and two of them did so. But George Eliot, still smarting from Spencer...
Autobiographical writings have been a major cultural genre from antiquity to the present time. General questions of the literary as, e.g., the relation between literature and reality, truth and fiction, the dependency of author, narrator, and figure, or issues of individual and cultural styles etc., can be studied preeminently in the autobiographical genre. Yet, the tradition of life-writing has, in the course of literary history, developed manifold types and forms. Especially in the globalized age, where the media and other technological / cultural factors contribute to a rapid transformation of lifestyles, autobiographical writing has maintained, even enhanced, its popularity and importanc...