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Graduate students in neuroanatomy, neurochemistry, neurophysiology, and molecular neurobiology will find the book indispensable. It is also a vital companion for researchers in these fields as well as clinicians in neurology, neurosurgery, neuropathology, neuro-oncology, physiatry, and psychiatry."--BOOK JACKET.
Inflammation of the brain in the context of neurodegenerative disorders is an area of intense debate and discussion, not least in terms of its pathogenic significance and the extent to which it drives disease processes and pathology. This inflammation can take several forms including innate responses recruiting microglia, humoral responses involving antibody, complement mediated processes and cellular T-cell activation, of which the role and extent of each may differ between diseases. Whilst some diseases have been more intensely linked to inflammation and long-term degeneration (e.g. MS), more traditional chronic neurodegenerative disorders have been thought of in terms of intrinsic neurona...
Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.
The study of microglial cells has recently gained importance for those researching degeneration and regeneration. Microglia in the regenerating and degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and reviews their cell function and physiology.
This thoroughly revised, extended and updated edition of a critically acclaimed textbook provides an accessible and cohesive introduction to the burgeoning discipline of institutional economics. Requiring only a basic understanding of economics, this lucid and well-written text will be essential reading for undergraduate and postgraduate students wanting to understand the problems of the real world Ð such as entrepreneurship, innovation, the cost of the welfare state, international financial crises, and economic development. As institutional economics is now revolutionising policy making, the book can also serve as a guide to the pressing problems facing policy makers in mature and emergent countries alike. Key features include: ¥ A short ÔPrimerÕ at the beginning of each chapter to highlight the main issues and their relevance. ¥ Key Concepts such as ÔinstitutionsÕ, Ôeconomic orderÕ, Ôcoordination costsÕ, ÔcompetitionÕ and Ôpublic policyÕ are highlighted and clearly defined. ¥ International coverage is ensured as the three authors, experienced academic teachers, work in the US, Europe and the Asia Pacific.
Neuroglia, the third edition, is the long-awaited revision of the most highly regarded reference volume on glial cells. This indispensable edition has been completely revised, greatly enlarged, and enhanced with four-color figures throughout, all in response to the tremendous amount of new information that has accumulated since the previous edition seven years ago. Glial cells are, without doubt, the new stars in the neuroscience and neurology communities. Neglected in research for years, it is now evident that the brain only functions in a concerted action of all the cells, namely glia and neurons. Seventy one chapters comprehensively discuss virtually every aspect of normal glial cell anat...
1 The Bermuda Triangle 2 The Little Girl Too Good to Be True 3 Stress and Emotional Competence 4 Buried Alive 5 Never Good Enough 6 You Are Part of This Too, Mom 7 Stress, Hormones, Repression and Cancer 8 Something Good Comes Out of This Is There a "Cancer Personality"? 10 The 55 Per Cent Solution 11 It's All in Her Head 12 I Shall Die First from the Top 13 Self or Non-Self: The Immune System Confused 14 A Fine Balance: The Biology of Relationships 15 The Biology of Loss 16 The Dance of Generations 17 The Biology of Belief 18 The Power of Negative Thinking 19 The Seven A's of Healing Notes Resources Acknowledgments Index
Presents the latest research findings on and introduces new research techniques for the study of the effects of alcohol on glial cells. Includes reviews of research findings and techniques used to study astrocytes, oligodendroglia, and microglia; findings on the influence of alcohol on glial cells during development; the role of astrocytes in alcohol-induced damage of the neuroimmune system; the role of glial cells in alcohol-induced neuropathology; the involvement of astrocytes in hepatic encephalopathy; new imaging techniques capable of separating glial and neuronal images in alcohol-induced brain atrophy; and information on alcoholic-induced disturbances in neurosteroid production by glial cells.
The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike.Comprehensive protocols included for the study of: - The brain-immune system - The neuroimmune system: Effects of the brain on the peripheral immune system - Neuroimmune effects from substances of abuse (e.g. cocaine) to hypnosis - Measurement of interferons, cytokines, natural killer cells, and major histocompatibility complex molecules - Immunohistochemistry methods in the brain - Neuropeptides as immunomodulators
Includes bibliographical references and index.