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Emerging Trends in Civil Engineering
This book comprises select papers from the International Conference on Emerging Trends in Civil Engineering (ICETCE 2018). Latest research findings in different branches of civil engineering such as structural engineering, construction materials, geotechnical engineering, water resources engineering, environmental engineering, and transportation infrastructure are covered in this book. The book also gives an overview of emerging topics like smart materials and structures, green building technologies, and intelligent transportation system. The contents of this book will be beneficial for students, academicians, industrialists and researchers working in the field of civil engineering.
New Developments in Sensing Technology for Structural Health Monitoring
The book has focussed on the different aspects of sensing technology, i.e. high reliability, adaptability, recalibration, information processing, data fusion, validation and integration of novel and high performance sensors specifically aims to use to inspect mechanical health of structure and similar applications. This book is dedicated to Sensing systems for Structural Health Monitoring offers to variety of users, namely, Master and PhD degree students, researchers, practitioners, especially Civil and Construction engineers. The book will provide an opportunity of a dedicated and a deep approach in order to improve their knowledge in this specific field.
Reconstructing Urban Ambiance in Smart Public Places
New technologies have the power to augment many aspects of society, including public spaces and art. The impact of smart technology on urban design is vast and filled with opportunity and has profound implications on the everyday urban environment. Only by starting new conversations can we develop further contemporary insights that will affect how we move through the world. Reconstructing Urban Ambiance in Smart Public Places is a pivotal reference source that provides contemporary insights into a comprehensive interpretation of urban ambiances in smart places as it relates to the development of cities or to various levels of intervention in extant urban environments. The book also examines ...
Dopamine and Glutamate in Psychiatric Disorders
An illuminating summary of our current understanding of the interactive role of dopamine and glutamate in psychiatric diseases and the therapeutic strategies and possibilities for future treatment. Among the new ideas presented are hypotheses on the role of dopamine and glutamate in aggression, the glutamate system in anxiety disorders, glutamate and neurodegeneration, and on the origin and progression of Parkinson's disease. Additional chapters offer novel insights into a variety of psychiatric diseases, including ADHD, stress, aggression, addiction, schizophrenia, depression, social phobias, dementias, bulimia, and neurodegenerative diseases like Parkinson's and Alzheimer's diseases. Each chapter summarizes the prevalence and symptoms of the disease and explains the involvement of dopamine and/or glutamate systems using the newer molecular approaches such as transgenic knockout or knockin mice and recent brain imaging techniques.
Human Retrotransposons in Health and Disease
This unique book explores the role of retrotransposons in human health and disease. The ability of retrotransposons to affect the structure of human genes is recognized since the late 80’s. However, the advances of deep-sequencing technologies have shed new light on the extent of retrotransposon-mediated genome variations. These progresses have also led to the discovery that retrotransposon activity is not restricted to the germline - resulting in inheritable genetic variations - but can also mobilize in somatic tissues, such as embryonic stem cells, neuronal progenitor cells, or in many cancers. This book covers topics related to the effects of retrotransposon insertions, and their consequences on germline and somatic genome dynamics, but also discuss the role and impact of retrotransposons sequences in a broader context, including a number of novel topics that emerged recently (long non-coding RNA, neuronal disorders, exaptation) with unexpected connections between retrotransposons, stem cell maintenance, placentation, circadian cycles or aging.
Plant Transposable Elements
This new volume provides an up-to-date understanding of the numerous classes of plant transposable elements, the mobile units of DNA that comprise large portions of plant genomes, which are an important contributor for gene and genome evolution. Transposable elements (TEs) are major components of large plant genomes and main drivers of genome evolution, known to produce a wide variety of changes in plant gene expression and function. Providing a systematic interpretation of protocols designed to characterize TEs and their biotechnological roles, the volume explores TEs in plant development, their architecture, their epigenetic regulation, their use in DNA repair, their evolution and speciati...
Advances in Geroscience
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of...
Lactic Acid Bacteria in Foodborne Hazards Reduction
This book provides an overview of the physiological basis of lactic acid bacteria and their applications in minimizing foodborne risks, such as pathogens, heavy metal pollution, biotoxin contamination and food‐based allergies. While highlighting the mechanisms responsible for these biological effects, it also addresses the challenges and opportunities that lactic acid bacteria represent in food safety management. It offers a valuable resource for researchers, graduate students, nutritionists and product developers in the fields of food science and microbiology.
Fundamentals Of Accountancy For C.A.Professional Education Course-1
In A Simple Style, This Book Presents A Systematic Account Of The Various Principles, Methods And Techniques Of Modern Accountancy. The Book Completely Covers The New Syllabus (November 2001) Prescribed By The Institute Of Chartered Accountants Of India.Important Features * Based On New Syllabus Of C.A. Professional Education Course-I. * Explains The Various Accounting Principles And Concepts In A Simple Language And Illustrates Them With Suitable Examples. * Important Terms And Standards Highlighted Throughout The Book. * Includes Several Solved Question Papers Of Previous C.A. Entrance And C.A. Foundation Examinations. * Also Includes Objective And Descriptive Questions With Answers At The End Of Each Chapter.This Book Would Serve As A Comprehensive Text For C.A. Candidates, Icwa (Inter) Candidates As Well As B. Com. Students Would Also Find It Extremely Useful.
PI3K signalling
The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the role of this pathway in cells of the immune system has been made in recent years, starting with analysis of various PI3K and Pten knockout mice and subsequently mTOR and Foxo knockout mice. Together, these experiments have revealed how PI3Ks control B cell and T cell development, T helper cell differentiation, regulatory T cell development and function, B cell and T cell trafficking, immunoglobulin class switching and much, much more. The PI3Kd inhibitor idelalisib has recently been approved for the treatment of B cell lymphoma. Clinical trials of other PI3K inhibitors in autoimmune and inflammatory diseases are also in progress. This is an opportune time to consider a Research Topic considering when what we have learned about the PI3K signalling module in lymphocyte biology and how this is making an impact on clinical immunology and haematology.
