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To survive in the host cells, viruses have to adapt various strategies, which include the modulation of microRNA (miRNA) pathway through virus-encoded miRNAs to modulate the host cellular environment. It has been shown that several avian viruses, mostly herpesviruses, encode a number of miRNAs. These include 26 miRNAs encoded by the highly oncogenic Marek,Äôs disease virus-1, 36 miRNAs encoded by avirulent Marek,Äôs disease virus-2, 28 miRNAs by herpesvirus of turkeys, 10 miRNAs by infectious laryngotracheitis virus, 41 miRNAs by duck enteritis virus, and 2 miRNAs by avian leukosis virus subgroup J.¬†Although locations of some of the miRNAs are conserved within the repeat regions of t...
Noncoding RNAs (ncRNAs) are an attractive research field in the RNA world. ncRNAs play important roles in regulating gene expression in animals, plants, and various human diseases. It is clear that current and further research on ncRNAs will change our knowledge of the nature of genome composition by editing previous dogmas. This book provides an overview of current knowledge on ncRNA research by dealing with miRNA and ncRNA-related human diseases, plant miRNA markers, and the roles of lncRNAs in cancer and epigenetics.
MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics. Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research.
Thirty years ago, the Chinese Communist Party (CCP) made a fateful decision: to allow newspapers, magazines, television, and radio stations to compete in the marketplace instead of being financed exclusively by the government. The political and social implications of that decision are still unfolding as the Chinese government, media, and public adapt to the new information environment. Edited by Susan Shirk, one of America's leading experts on contemporary China, this collection of essays brings together a who's who of experts--Chinese and American--writing about all aspects of the changing media landscape in China. In detailed case studies, the authors describe how the media is reshaping it...
Molecular Detection of Animal Viral Pathogens presents expert summaries on state-of-the-art diagnostic approaches for major animal viral pathogens, with a particular emphasis on identification and differentiation at the molecular level. Written by specialists in related research areas, each chapter provides a concise overview of an individual virus
The Buddhist master Fazang is regarded as one of the greatest metaphysicians in medieval Asia. This study aims at correcting misinterpretations and shedding light on neglected areas, opening up for discussion the various structures of medieval East Asian monastic biography.