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This book will focus on DNA and histone methylation in epigenetics and describe how it is involved in the molecular mechanisms responsible for the development of cancer. Chapters will summarize the current knowledge of the molecular basis of DNA and histone methylation and explain how it is involved in cancer, describe the features of DNA and histone methylation associated with particular types of cancer, diagnostic/therapeutic applications, and future directions of DNA and histone methylation as cancer targets.
In 1603, Queen Elizabeth I died and King James I inherited the English throne. During James's reign, England continued to hark back to Elizabeth, comparing him with his predecessor – not always in a way that was either flattering or pleasing to James. Critics have traditionally assumed that Shakespeare avoided involving himself in this discourse. In this study of Shakespeare's Jacobean plays, however, Yuichi Tsukada demonstrates that, far from not involving himself in the phenomenon of nostalgia for Elizabeth, Shakespeare interacted closely with retrospective writings on Elizabeth and illuminated the complex politics behind the nostalgia. Based upon close readings of Macbeth, Antony and Cl...
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"In the second half of the twentieth century, Reiki went from an obscure therapy practiced by a few thousand Japanese and Japanese Americans to a global phenomenon. By the early twenty-first century, people in nearly every corner of the world have undergone the initiations that authorize them to channel a cosmic energy--known as Reiki--to heal body, mind, and spirit. They lay hands on themselves and others, use secret symbols and incantations to send Reiki to distant recipients, and strive to follow five precepts to cultivate their spiritual growth. Reiki's international rise and development is due to the work of Hawayo Takata (1900-1980), a Hawai°i-born Japanese American woman who brought ...
This collection focuses on ferrous and non-ferrous metallurgy where ionic melts, slags, fluxes, or salts play important roles in industrial growth and economy worldwide. Technical topics included are: thermodynamic properties and phase diagrams and kinetics of slags, fluxes, and salts; physical properties of slags, fluxes, and salts; structural studies of slags; interfacial and process phenomena involving foaming, bubble formation, and drainage; slag recycling, refractory erosion/corrosion, and freeze linings; and recycling and utilization of metallurgical slags and models and their applications in process improvement and optimization. These topics are of interest to not only traditional ferrous and non-ferrous metal industrial processes but also new and upcoming technologies.
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