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Index of Patents Issued from the United States Patent and Trademark Office
  • Language: en
  • Pages: 1574

Index of Patents Issued from the United States Patent and Trademark Office

  • Type: Book
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  • Published: 1987
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  • Publisher: Unknown

None

Tumor Antigens Recognized by T Cells and Antibodies
  • Language: en
  • Pages: 330

Tumor Antigens Recognized by T Cells and Antibodies

  • Type: Book
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  • Published: 2003-01-23
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  • Publisher: CRC Press

Recent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens c

Cell Therapy
  • Language: en
  • Pages: 220

Cell Therapy

Modern cell biology has brought improvements in therapy for advanced malignant diseases through immunomodulation, hematopoietic stem cell transplantation, and other advanced techniques. Collected here are selected papers from the Fifth International Symposium of Keio University for Life Sciences and Medicine on Cell Therapy. All chapters include innovative basic research for clinical application: immunotherapy, cancer vaccination, molecular biology of hematopoietic stem cells, stem cell processing, and gene therapy. The book is divided into three parts: Immunotherapy for malignant diseases; Hematopoietic stem cell biology and clinical application; and International collaboration in hematopoietic stem cell transplantation. Included in the third part is information on bone marrow registries from around the world. The book thus presents up-to-date information on biological and clinical aspects of treatment, with insight into the future of cell therapy.

Cancer Immunotherapy & Immuno-monitoring: Mechanism, Treatment, Diagnosis, and Emerging Tools
  • Language: en
  • Pages: 98

Cancer Immunotherapy & Immuno-monitoring: Mechanism, Treatment, Diagnosis, and Emerging Tools

In the past decade, significant progresses have taken place in the field of cancer immunotherapy. Tumor-targeting immunotherapies are being developed for most human cancers, including melanoma, prostate cancer, glioblastoma, sarcoma, lung carcinoma and hepatocellular carcinoma. The FDA has approved multiple molecular immunotherapeutics, such as Ipilimumab; cellular immunotherapies (e.g. adoptive cell transfer) are being tested in phase II/III clinical trials. Immunotherapetics has evolved into a sophisticated field: Multimodal therapeutic regimens are administrated to induce focused responses, curtail side- effects and improve therapeutic efficacy. The lack of effective clinical assessment t...

Index of Patents Issued from the United States Patent Office
  • Language: en
  • Pages: 2026

Index of Patents Issued from the United States Patent Office

  • Type: Book
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  • Published: 1983
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  • Publisher: Unknown

None

Molecular Diagnosis of Cancer
  • Language: en
  • Pages: 389

Molecular Diagnosis of Cancer

We are currently experiencing a fundamental shift in the way in which we approach the characterization of cancer. Never before has the make up of cancer tissues and individual cells been so exhaustively researched and char- terized. We are now capable of producing molecular “fingerprints” that ch- acterize the expression of all known and unknown genes within tumors and their surrounding tissues. More than 30,000 different genes may be measured in each patient’s tumor in a single experiment. Simultaneously, novel therapies that exploit the molecular roadmap have been developed and are now being offered to patients. These novel agents, such as Glivec, Herceptin, Iressa, and others, speci...

Innate Immune Regulation and Cancer Immunotherapy
  • Language: en
  • Pages: 476

Innate Immune Regulation and Cancer Immunotherapy

Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: inhibiting or promoting tumor growth and progression. Although regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against self- or non self-antigens, thus playing critical roles in preventing autoimmune diseases, they might inhibit antitumor immunity and promote tumor growth. Recent studies demonstrate that elevated proportions of Treg cells are present in various types of cancers and suppress antitumor immunity. Furthermore, tumor-specific Treg cells can inhibit immune responses only when they are exposed to antigens presented by tumor cells. Therefore, Treg cells at tumor sites have detrimental effects on immunotherapy directed to cancer.

Progress Report
  • Language: en
  • Pages: 372

Progress Report

  • Type: Book
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  • Published: 1992
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  • Publisher: Unknown

None

Official Gazette of the United States Patent and Trademark Office
  • Language: en
  • Pages: 1376

Official Gazette of the United States Patent and Trademark Office

  • Type: Book
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  • Published: 2001
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  • Publisher: Unknown

None

Development of Humanized Mouse Models for Infectious Diseases and Cancer
  • Language: en
  • Pages: 169