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Molecular Mechanisms of Neurotransmitter Release
Neurons communicate with each other by releasing neurotransmitters. This book provides comprehensive coverage of the molecular mechanisms involved in neurotransmitter release. The topics covered in the book range from the architecture and cytomatrix proteins of presynaptic sites, to the modes of synaptic vesicle exocytosis (full-collapse and kiss-and-run), and from the key molecules mediating synaptic vesicle fusion (SNAREs) to those that closely interact with them (UNC-13/Munc13, UNC-18/Munc18, tomosyn, and complexins). The book also delves into the calcium sensors of synaptic vesicle fusion (synaptotagmins and Doc2s), the sources of calcium that trigger synaptic exocytosis (voltage-gated c...
His Stubbornship: Prime Minister Wang Anshi (1021--1086), Reformer and Poet
China’s most controversial prime minister, path-breaking reformer, and an iconic Song-dynasty poet, Wang Anshi (1021—1086) is fully chronicled in English for the first time in almost a century, with a new emphasis on his luminous late verse.
Check Dam Construction for Sustainable Watershed Management and Planning
CHECK DAM CONSTRUCTION FOR SUSTAINABLE WATERSHED MANAGEMENT AND PLANNING Authoritative and comprehensive reference on the potential for watershed development through the use of check dams Check Dam Construction for Sustainable Watershed Management and Planning summarizes current knowledge of check dams as key soil and water conservation structures in some of the most sensitive and vulnerable ecosystems in the world, as exemplified by the Mediterranean area and the Chinese Loess Plateau, providing detailed information on check dam design and watershed planning, the use of advanced modeling techniques, challenges in dam construction and how to overcome them. The work integrates decades of rese...
China Twenty-four Histories (Complete Translation)
The Twenty-Four Histories (Chinese: 二十四史) are the Chinese official historical books covering a period from 3000 BC to the Ming dynasty in the 17th century. The Han dynasty official Sima Qian established many of the conventions of the genre. Starting with the Tang dynasty, each dynasty established an official office to write the history of its predecessor using official court records. As fixed and edited in the Qing dynasty, the whole set contains 3213 volumes and about 40 million words. It is considered one of the most important sources on Chinese history and culture. The title "Twenty-Four Histories" dates from 1775 which was the 40th year in the reign of the Qianlong Emperor. This ...
Molecular Mechanisms of Neurotransmitter Release
Neurons in the nervous system organize into complex networks and their functions are precisely controlled. The most important means for neurons to communicate with each other is transmission through chemical synapses, where the release of neurotransmitters by the presynaptic nerve terminal of one neuron influences the function of a second neuron. Since the discovery of chemical neurotransmission by Otto Loewi in the 1920s, great progress has been made in our understanding of mol- ular mechanisms of neurotransmitter release. The last decade has seen an explosion of knowledge in this field. The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage ...
Officialdom Unmasked
It has been said that the downfall of the Qing dynasty was due not so much to the 1911 Revolution as to the pervasive corruption and weakness within the Qing administration. The regime was rotting from within, and it did not take much to topple the three-hundred-year-old dynasty. Officialdom Unmasked (官場現形記) was written by Li Boyuan in the early years of the twentieth century as the dynasty crumbled. Bizarre though they may seem, the stories told in the novel are based on true stories. From senior ministers to junior clerks, few were immune from taking bribes, stealing, philandering, dereliction of duty, or other wrongdoings. Here the writer portrays an official class who placed their selfish interests above that of the state, and who were so devoid of any moral rectitude that one could but wonder how a once mighty empire had fallen into so complete a decline. Unlike most satires, often written with a degree of humour which evoke a chuckle here and there, this work came from a broken heart; it brings only tears, not smiles.
Strategies of the Warring States
The Zhan Guo Ce, also known in English as the Strategies of the Warring States, is an ancient Chinese text that contains anecdotes of political manipulation and warfare during the Warring States period (5th to 3rd centuries bc).[1] It is an important text of the Warring States Period as it describes the strategies and political views of the School of Diplomacy and reveals the historical and social characteristics of the period. The Zhan Guo Ce recounts the history of the Warring States from the conquest of the Fan clan by the Zhi clan in 490 BC up to the failed assassination of Qin Shi Huang by Gao Jianli in 221 BC. The chapters take the form of anecdotes meant to illustrate various strategi...
From the Khitans to the Jurchens & Mongols
From the Khitans to the Jurchens & Mongols, A History of Barbarians in Triangle Wars & Quartet Conflicts is the third book of The Scourge of God Tetralogy. This is a book with comprehensive writeup of the barbarians’ history spanning more than one thousand years, from before the anno domini eras and inclusive of the expulsion of the Mongols from China. The subtitle about the barbarians in triangle wars & quartet conflicts is self-explanatory for the historical environment of different groups of barbarians successively rising up on the steppes to overpower the former with more savagery. This third book, while carrying a title with emphasis on the Khitans, the Jurchens and Mongols, also cove...
Advances in Tourism, Technology and Systems
This book features a collection of high-quality research papers presented at the International Conference on Tourism, Technology & Systems (ICOTTS 2020), held at the University of Cartagena, in Cartagena de Indias, Colombia, from 29th to 31st October 2020. The book is divided into two volumes, and it covers the areas of technology in tourism and the tourist experience, generations and technology in tourism, digital marketing applied to tourism and travel, mobile technologies applied to sustainable tourism, information technologies in tourism, digital transformation of tourism business, e-tourism and tourism 2.0, big data and management for travel and tourism, geotagging and tourist mobility, smart destinations, robotics in tourism, and information systems and technologies.
