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Daughters of Emptiness
Women played major roles in the history of Buddhist China, but given the paucity of the remaining records, their voices have all but faded. In Daughters of Emptiness, Beata Grant renders a great service by recovering and translating the enchanting verse - by turns assertive, observant, devout - of forty-eight nuns from sixteen centuries of imperial China. This selection of poems, along with the brief biographical accounts that accompany them, affords readers a glimpse into the extraordinary diversity and sometimes startling richness of these women's lives. A sample poem for this stunning collection: The sequence of seasons naturally pushes forward, Suddenly I am startled by the ending of the...
ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
Economic Stress, Human Capital, and Families in Asia
This book presents recent findings about the consequences and policy implications of economic stress for human capital development and family well-being in Asia. The scope of the chapters goes beyond the impact of current financial crisis to include the effect of economic deprivation families in Asia experience as a result of job loss, low-wage employment, and catastrophic natural calamities. The studies show how macro-level economic stress can filter down through households to affect individuals’ economic and socio-psychological well-being. The chapters reveal a wide spectrum of economic stresses experienced by families in Asia that is linked to poor human capital development, emotional d...
Proceedings of the 2023 8th International Conference on Engineering Management (ICEM 2023)
This is an open access book.ICEM started in 2016, ICEM 2016-2022 is to bring together innovative academics and industrial experts in the field of Engineering Management to a common forum. And we achieved the primary goal which is to promote research and developmental activities in Engineering Management, and another goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working all around the world. 2023 8th International Conference on Engineering Management (ICEM 2023) will be held on September 8-10, 2023 in Wuhan, China. Except that, ICEM 2023 is to bring together innovative academics and industrial experts in the field...
Cultural Perspectives on Shame
Each essay in this volume provides a cultural perspective on shame. More specifically, each chapter focuses on the question of how culture can differentially affect experiences of shame for members of that culture. As a collection, this volume provides a cross-cultural perspective on shame, highlighting the various similarities and differences of experiences of shame across cultures. In Part 1, each contributor focuses primarily on how shame is theorized in a non-English-speaking culture, and address how the science of shame ought to be pursued, how it ought to identify its object of study, what methods are appropriate for a rigorous science of shame, and how a method of study can determine ...
Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases
Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, distribution, metabolism and excretion (ADME) of therapeutic proteins as well as translational pharmacokinetic/pharmacodynamic (PK/PD) modeling for them. This comprehensive volume answers that need to be addressed. Featuring eighteen chapters from world-renowned experts and opinion leaders in pharmacology, translational...
Eminent Nuns
The seventeenth century is generally acknowledged as one of the most politically tumultuous but culturally creative periods of late imperial Chinese history. Scholars have noted the profound effect on, and literary responses to, the fall of the Ming on the male literati elite. Also of great interest is the remarkable emergence beginning in the late Ming of educated women as readers and, more importantly, writers. Only recently beginning to be explored, however, are such seventeenth-century religious phenomena as "the reinvention" of Chan Buddhism—a concerted effort to revive what were believed to be the traditional teachings, texts, and practices of "classical" Chan. And, until now, the ro...
