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Text by Jason C. Kuo.
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
This book comprises select peer-reviewed proceedings of the 6th International Conference on Innovative Computing (IC 2023). The contents focus on communication networks, business intelligence and knowledge management, web intelligence, and fields related to the development of information technology. The chapters include contributions on various topics such as databases and data mining, networking and communications, web and Internet of Things, embedded systems, soft computing, social network analysis, security and privacy, optical communication, and ubiquitous/pervasive computing. This volume will serve as a comprehensive overview of the latest advances in information technology for those working as researchers in both academia and industry.
Electromagnetic metamaterials are a family of shaped periodic materials which achieve extraordinary scattering properties that are difficult or impossible to achieve with naturally occurring materials. This book focuses on one such feature of electromagnetic metamaterials—the theory, properties, and applications of the absorption of electromagnetic radiation. We have written this book for undergraduate and graduate students, researchers, and practitioners, covering the background and tools necessary to engage in the research and practice of metamaterial electromagnetic wave absorbers in various fundamental and applied settings. Given the growing impact of climate change, the call for innov...
This handbook in two parts covers key topics of the theory of financial decision making. Some of the papers discuss real applications or case studies as well. There are a number of new papers that have never been published before especially in Part II.Part I is concerned with Decision Making Under Uncertainty. This includes subsections on Arbitrage, Utility Theory, Risk Aversion and Static Portfolio Theory, and Stochastic Dominance. Part II is concerned with Dynamic Modeling that is the transition for static decision making to multiperiod decision making. The analysis starts with Risk Measures and then discusses Dynamic Portfolio Theory, Tactical Asset Allocation and Asset-Liability Manageme...
The proper detection of stimuli coming from the environment is vital for any organism, in vertebrates as in invertebrates. Animals use different sensory modalities, independently or simultaneously, to detect them, such as audition, vision, olfaction, taste and touch. Indeed, in their ecosystems, animals constantly perceive various sensory signals. These stimuli come either from the environment (light, temperature, humidity, salinity...), or from other organisms (calls, colors, movements, pheromones, allomones, ...). This eBooks combines studies and comments (research articles, reviews, opinions ...), dealing with how animals detect a precise simple or complex sensory signal, confer a value to that signal, and respond to it by devoted and adaptive behaviors. This eBook provides a general overview for the detection of identified stimuli, and the mechanisms that lead to decision-making in animals. It also highlights the differences and similarities that may exist between vertebrates and invertebrates.