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Vitamin D Analogs in Cancer Prevention and Therapy
A comprehensive, highly readable overview of the topics discussed at the First International Symposium on "Vitamin D Analogs in Cancer Prevention and Therapy" held in Homburg/Saar, Germany in May 2002. Leading researchers discuss our present knowledge of the vitamin D system in cancer. Topics range from the newest findings in molecular biology, epidemiology, synthesis and metabolism of vitamin D to new concepts for the use of vitamin D analogs in cancer prophylaxis and treatment. The book provides essential up-to-date information for every researcher or clinician interested in the biology of vitamin D or cancer.
Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions
There is a high prevalence of vitamin D deficiency worldwide, but how to define vitamin D deficiency is controversial. Currently, the plasma concentration of total 25-hydroxyvitamin D [25(OH)D] is considered an indicator of vitamin D status. The free hormone hypothesis states that protein-bound hormones are inactive while unbound hormones are free to influence biological activity. The majority of circulating 25(OH)D and 1,25(OH)2D is tightly bound to vitamin D binding protein (DBP), 10 -15% is bound to albumin, and less than 1% of circulating vitamin D exists in an unbound form. While DBP is relatively stable in most healthy populations, recent studies have shown that there are gene polymorphisms associated with race and ethnicity that could alter DBP levels and binding affinity. Furthermore, in some clinical situations total 25(OH)D levels are altered, and knowing whether DBP is also altered may have implications for diagnosis and treatment. In this Research Topic, we provide a collection of comprehensive research on vitamin D and DBP metabolism among different ethnic population and patients with different diseases.
Sunlight, Vitamin D and Skin Cancer
The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
NIH News & Features
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The proceedings of the 16th Annual Conference of China Electrotechnical Society
This book gathers outstanding papers presented at the 16th Annual Conference of China Electrotechnical Society, organized by China Electrotechnical Society (CES), held in Beijing, China, from September 24 to 26, 2021. It covers topics such as electrical technology, power systems, electromagnetic emission technology, and electrical equipment. It introduces the innovative solutions that combine ideas from multiple disciplines. The book is very much helpful and useful for the researchers, engineers, practitioners, research students, and interested readers.
Chinese Fiction of the Cultural Revolution
The book covers the choice of subject matter, authorship and readership of Cultural Revolution fiction. It analyses the characterization of heroes promoted in the literary and artistic field during this period. By comparing Cultural Revolution fiction with the fiction of the preceding period, with Soviet fiction, and with some traditional Chinese and Western fiction, this analysis emphasizes the ideological and cultural significance of the characteristics shown in the heroes personal background and their physical, temperamental and behavioural qualities, etc. This book will be of significant benefit to both students and scholars of Chinese literature, language and society.
