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Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlyin...
B�uerliche Agrarrevolutionen pr�gten Europas Neuzeit und Industrialisierung. Bis heute fehlt jedoch eine befriedigende Erkl�rung fuer die �konomische Vitalit�t der neuzeitlichen Bauern. Wichtige Beitr�ge bietet die neuere Entwicklungs�konomie mit ihrer radikalen Neubewertung der Leistungs- und Modernisierungsf�higkeit b�uerlichen Wirtschaftens. Der vorliegende Band nutzt erstmals systematisch entwicklungs�konomische Erkenntnisse fuer eine vergleichende Analyse der neuzeitlichen englischen und westf�lischen Agrarentwicklung. Dabei zeigt sich, dass sich industrielle und zeitnahe agrarische �Revolutionen� fundamental unterschieden. Dennoch stellten die neuzeitlichen Agrarrevolutionen den Durchbruch in die moderne Welt dar. Entscheidend hierfuer war die ausgepr�gte Anpassungsf�higkeit b�uerlicher �konomie an sich best�ndig wandelnde M�rkte.
In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic intervent...
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An edited volume by Monsoon Assemblages, a European Research Council funded research project. The book presents the methods that Monsoon Assemblages has evolved for engaging the monsoon, a globally connected weather system, as a coproducer of urban life and space in South and Southeast Asian cities. It challenges views of climate as an inert backdrop to urban life, instead suggesting that it is materially and spatially active in shaping urban politics, ecologies, infrastructures, buildings and bodies. It combines critical texts with cartography, photography and ethnography to present the project’s methodology and its outcomes and invites urban practitioners to think differently about space, time, representation and human and non-human agency. It offers intra-disciplinary, intra-active methods for rethinking human and non-human relations with weather in ways that meet the challenges of climate change and the Anthropocene.
Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.
Sixteenth in a series of annual reports comparing business regulation in 190 economies, Doing Business 2019 measures aspects of regulation affecting 10 areas of everyday business activity: • Starting a business • Dealing with construction permits • Getting electricity • Registering property • Getting credit • Protecting minority investors • Paying taxes • Trading across borders • Enforcing contracts • Resolving insolvency These areas are included in the distance to frontier score and ease of doing business ranking. Doing Business also measures features of labor market regulation, which is not included in these two measures. This edition also presents the findings of the p...
Dieser Leitfaden richtet sich an C++-Programmierer, die sich mit dem C++11-Standard vertraut machen möchten. Er zeigt, welche Neuerungen und Erweiterungen der Standard mit sich bringt, wie die neuen Features effizient eingesetzt werden -- und warum C++11 das bessere C++ ist. Das Buch bietet zunächst einen Überblick über die C++11-Features und zeigt dann im Detail, wie Sie die Neuerungen in Ihren Programmen einsetzen können. Behandelt werden die Kernsprache, die Multithreading-Funktionalität sowie die Verbesserungen der Standardbibliothek. Der Autor verfolgt dabei einen praxisnahen Ansatz: Zahlreiche lauffähige Beispielprogramme, die Sie herunterladen können, sollen Sie zum Ausführen und auch zum Modifizieren des Codes ermutigen. Übungsaufgaben helfen Ihnen darüber hinaus, die Theorie optimal mit der Praxis zu verbinden, damit Sie C++11 in Zukunft erfolgreich anwenden können.
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