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Interstitial Fibrosis in Heart Failure, edited by Francisco J. Villarreal, M.D., Ph.D., provides a timely and integrative review of the basics of cardiac extracellular matrix structure. Topics covered include how cardiac remodeling influences its disposition, abundance and function; possible non-invasive techniques for diagnosis; and potential drug-based or molecular therapeutic strategies that may interrupt or even reverse the course of the development of cardiac fibrosis. This resource for both clinicians and scientists aims to cover state-of-the-art findings relevant to cellular and molecular processes underlying cardiac fibrosis including basic elements of structure, function, diagnosis and treatment.
There have been numerous significant developments for TPQ since 2022. Our recent rebranding as Transatlantic Policy Quarterly not only reflects our expanded focus on international issues with broad implications for European and American politics, but also incorporates a new vision for the future. Our most recent issues focused on various aspects of the broader challenges and possibilities presented by this new vision, and we gratefully received numerous contributions from our eminent authors. Although we have published some of these articles in previous issues, it was necessary to give the floor to other authors whose Opinion articles also made an outstanding contribution. Keeping this in mind, we have prepared this special issue, the primary objective of which is to give a collection of such remarkable works, including those that have been previously published digitally.
This volume, the result of the 21st Conference on Postal and Delivery Economics (Ireland, 2013), describes the continuing problem of the decline of the postal sector in the face of electronic competition and offers strategies for the survival of mail s
How is access to asylum and other forms of extraterritorial protection regulated in the European Union? Is the EU acquis in these areas in conformity with international law? Which tools does international law offer to solve collisions between both? And, finally, is law capable of bridging the foundational oppositions embedded in migration and asylum issues? This work combines the potential of legal formalism with an analytical framework drawing on political theory. It analyses the argumentative strategies used by international lawyers, and developed them further, exploiting the interpretative methodology of international law as well as elaborate discrimination arguments. The author concludes...
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This book is about the recently revived technique of Kock pouch in inflammatory bowel disease. It discusses the Kock pouch as an alternative to patients not suitable for a pelvic pouch or where the pelvic pouch has failed. It provides clinicians with all the necessary information on patient guidance and surgical revisions after a long life with a Kock pouch. The reader will learn about the development of the pouch, pre and post-operative strategies, surveillance, complications and the limitations and weaknesses of the method. New pioneering experimental methods used by the authors are also discussed. The use of ileorectal anastomosis and Kock’s continent ileostomy has regained interest as the long term problems of the pelvic pouch have and this book brings the knowledge and valuable experiences of a few experts at international centres to a large audience. This is an indispensable guide for colorectal surgeons, gastroenterologists and stoma therapi sts involved in the care of patients with inflammatory bowel disease where colectomy is still needed, either in an emergency setting or due to dysplasia or cancer.