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Discover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spread of infectious diseases. The next two parts highlight the most promising uses of molecular identification, ...
Jackson Hastings se stejně jako jeho předkové věnuje farmaření, ale stále ho to táhne do města. Z dědictví po babičce si proto ve městě zřídí obchod a začne podnikat. Zásnuby s Eloise, dcerou bohatého obchodníka s uměním, jeho venkovskou minulost nadobro uzavřou. Pak se ovšem do jeho života vrátí Melody, která Jacksona bláznivě milovala už od dětství, a všechno se začne komplikovat.
A comprehensive guide to the history and technology of transatlantic passenger ships. This book covers the earliest steam-powered liners, through the great ocean liners of the early 20th century, and up to the modern cruise ships of today. With photographs, diagrams, and detailed descriptions of the ships and their voyages, this book is a must-have for anyone interested in the history of ocean travel. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.
As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be the turning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.
The updated and expanded third edition of Tilly's widely acclaimed book brings this analytical history of social movements fully up to date. Tilly and Wood cover such recent topics as the economic crisis and related protest actions around the globe while maintaining their attention to perennially important issues such as immigrants' rights, new media technologies, and the role of bloggers and Facebook in social movement activities. With new coverage of colonialism and its impact on movement formation as well as coverage and analysis of the 2011 Arab Spring, this new edition of Social Movements adds more historical depth while capturing a new cycle of contention today. New to the Third Edition Expanded discussion of the Facebook revolution-and the significance of new technologies for social movements Analysis of current struggles-including the Arab Spring and pro-democracy movements in Egypt and Tunisia, Arizona's pro- and anti-immigration movements, the Tea Party, and the movement inspired by Occupy Wall Street Expanded discussion of the way the emergence of capitalism affected the emergence of the social movement.
«It is better one man dies than the whole nation perishes» (Jn 11: 50). Caiaphas' sentence goes beyond ethical principles and religious expectations. It appears as the saying of a cynic politician. Besides, it is seen as the perfidious advice of a corrupted high priest to the members of the Sanhedrin. Who is this man on whose saying a school is formed? Who is this man who played the most important role in the death of Jesus? Indeed Caiaphas' sentence gives rise to the following relevant question: is the prohibition of killing (Dt. 5: 17), even the killing of a single individual in order to save a whole nation, legitimate? Thus, many issues that are associated with this high priest are associated with Jesus. The book is mainly an exegetical and comparative analysis of Jn 11: 45-54 and the Akan myth of the crossing of the river. By providing new theological insights into Caiaphas link to Jesus' death, it gives pertinent answers to the above questions.
Byla přesvědčená, že její dospělé děti mají mezi sebou pěkné vztahy. Ale mýlila se. Nebo si to namlouvala, Dost možná si své děti jen slepě idealizovala... K osmdesátým narozeninám si bývalá učitelka Hermína Foretová přála jediné: strávit se syny a dcerou týden v hájence pod svatým Hostýnem, kam s nimi jezdila v čase jejich dětství. Jenže právě tam se všem oživí vzpomínky na tragédii, při níž rodina přišla o svého nejmladšího člena – pětiletého Prokopa. Jeho červená plyšová liška, kterou dostal v roce 1975 od rodičů k pátým narozeninám, začíná po letech rodinu děsit. Čeká na ně v hájence, aby sourozencům i jejich matce připomněla hrůznou minulost. Stará, vypelichaná hračka – která před dvaačtyřiceti lety nedobrovolně tancovala liščí tanec – je provokuje, dráždí a rozděluje. Se svou minulostí se pak musí všichni naučit žít, i když se rozjedou zpět do svých domovů. A stejně jako v dávných sedmdesátých letech, i teď platí, že někdo z nich za to zaplatí životem...
Vítejte ve světě, kde je 97hodinový pracovní týden. Vítejte ve světě, kde se dělají rozhodnutí o životě a smrti. Vítejte ve světě s nepřetržitou tsunami tělesných tekutin. Vítejte ve světě, kde vyděláváte míň než automat na nemocničním parkovišti. Dejte sbohem svým přátelům a vztahům. Vítejte v životě mladého lékaře. Když Adam Kay poprvé vkročil na nemocniční oddělení, rázem si uvědomil, že na medicíně je neučili spoustě věcí... Jeho deníky z první linie státního zdravotnictví – potají nadrápané po dlouhých nočních šichtách, nekonečných dnech a prošvihnutých víkendech – jsou střídavě legrační, děsivé a s...