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This book is a printed edition of the Special Issue "Snake Venom Metalloproteinases" that was published in Toxins
In 24 contributed chapters, 37 international specialists describe the latest developments in research on snake venom including different types of venoms and toxins, actions, antidotes, and applications and summarize what is known to date on Gila monster and frog toxins. Some 70 tables provide essent
Covering the most recent advances in our understanding of toxins from venomous animals and microbes as well as that of their targets, this book expertly addresses the many intriguing and unsolved questions concerning; proteomics studies of the "toxinome", intimate modes of toxin actions, molecular basis of specificity, pleiotropic properties of toxins and structural biology of toxins. Through twenty-seven chapters the authors discuss the role of structural genomics in toxinology, how toxins are subject to accelerated evolution, how toxins can be exploited as models for the design of new drugs, and what the future holds for the treatment of snake bites. In order to address these challenging aspects, the authors have posed crystal-clear questions. Based on the most precise knowledge the attendant reasoning shows how toxinology has become an important area of biochemistry and is directly associated with advances in cellular microbiology, molecular pharmacology, molecular physiology, cell biology, protein engineering and many other disciplines.
Life is a struggle on both land and in the sea and many animals have developed chemical weapons, for attack or defence. These toxins, venoms or poisons, are diverse in both structure and function and are delivered to victims in equally diverse ways. Humans frequently encounter these venomous and poisonous animals and all too often suffer unpleasant consequences including death, be it from a bite or sting causing envenoming, or poisoning after eating the wrong animal. The author, toxicologist at the Department of Forensic Science of the University of Frankfurt, Germany, provides expert information for biologists, toxicologists, pharmacists, physicians, but also for travelers.