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Science & Engineering Researches
Medicine and Health Sciences Researches
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This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block vira...
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Challenging new play by the enfant terrible of dark, disturbing drama Elliot is panicking. The party that he and his brother Darren have been planning has been brought forward - to tonight. In a lawless, ravaged city, where memories of the past have been brutally erased, the boys and their team survive by realising their clients' darkest fantasies. But just how far are they prepared to go in trading humanity for information? As the light fades and events spiral out of control it becomes clear that on the success of the evening hangs not just their security, but their existence. The world is at its worst...let the party begin. Mercury Fur is a challenging new work containing some explicit scenes that may cause offence. Published to tie-in with the play's premier at the Drum Theatre, Plymouth and The Chololate Factory, London in February 2005, produced by Paines Plough. "Philip Ridley is a singular writer, a prolific polymath, probably a genius, and the creator of some of the most peculiar, grotesque and compelling British plays (and films) of the last several years" Time Out