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Advances in Inorganic Chemistry
  • Language: en
  • Pages: 421

Advances in Inorganic Chemistry

Advances in Inorganic Chemistry

Metal Ions in Biological Systems
  • Language: en
  • Pages: 322

Metal Ions in Biological Systems

  • Type: Book
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  • Published: 1986-11-25
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  • Publisher: CRC Press

This volume focuses on the physical methods to probe the coordination sphere of metal ions in biological systems, which are based on para-magnetic species, namely, the electron nuclear double resonance (ENDOR), electron paramagnetic resonance (EPR), and electron spin echo (ESE) techniques.

Pharmacokinetics in Drug Development
  • Language: en
  • Pages: 325

Pharmacokinetics in Drug Development

The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug development project teams. They regard the practical considerations for assessment of selected special development populations. For example, they include characterization of drug disposition in pregnant subjects, for measuring arrhythmic potential, for analysis tumor growth modeling, and for disease progression modeling. Practical considerations for metabolite safety testing, transporter assessments, Phase 0 testing, and development and execution of drug interaction programs reflect current regulatory topics meant to address enhancement of both safety assessment and early decision-making during new candidate selection. Important technologies like whole body autoradiography, digital imaging and dried blood spot sample collection methods are introduced, as both have begun to take a more visible role in pharmacokinetic departments throughout the industry.

Clinical Pharmacology: Current Topics and Case Studies
  • Language: en
  • Pages: 438

Clinical Pharmacology: Current Topics and Case Studies

Today we witness an eventful time in which the powerful new forces of genomics, information technology and economics are rapidly changing the science and art of medicine. This will require more specialization than ever before. However, there is also an increasing demand for an integrated approach, which is provided by the discipline of Clinical Pharmacology (CP). CP pursues a scientific goal by studying drug action in patients and volunteers, a clinical goal by administering appropriate drug therapy and a regulatory goal by assessing the risk/benefit ratio of drug candidates in drug development and reimbursement. This introduction to current topics of CP covers traditional topics of clinical drug research and trial methodology but also provides insight in current topics like genomics, imaging technology and issues in drug reimbursement. A number of concrete case studies in clinical drug research and development help to give a better understanding of the general principles of CP.

Comprehensive Coordination Chemistry II
  • Language: en
  • Pages: 11845

Comprehensive Coordination Chemistry II

  • Type: Book
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  • Published: 2003-12-03
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  • Publisher: Newnes

Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.

Integrated Approach to Coordination Chemistry
  • Language: en
  • Pages: 290

Integrated Approach to Coordination Chemistry

Coordination chemistry is the study of compounds formed between metal ions and other neutral or negatively charged molecules. This book offers a series of investigative inorganic laboratories approached through systematic coordination chemistry. It not only highlights the key fundamental components of the coordination chemistry field, it also exemplifies the historical development of concepts in the field. In order to graduate as a chemistry major that fills the requirements of the American Chemical Society, a student needs to take a laboratory course in inorganic chemistry. Most professors who teach and inorganic chemistry laboratory prefer to emphasize coordination chemistry rather than attempting to cover all aspects of inorganic chemistry; because it keeps the students focused on a cohesive part of inorganic chemistry, which has applications in medicine, the environment, molecular biology, organic synthesis, and inorganic materials.

Directory of Graduate Research
  • Language: en
  • Pages: 1932

Directory of Graduate Research

  • Type: Book
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  • Published: 2005
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  • Publisher: Unknown

Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

The World of Visual Time Signals for Mariners
  • Language: en
  • Pages: 467

The World of Visual Time Signals for Mariners

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Reflections on the Astronomy of Glasgow
  • Language: en
  • Pages: 391

Reflections on the Astronomy of Glasgow

This engrossing and entertaining scientific history includes the story of Glasgow's 'Big Bang' of 1863, the controversy over 'Astronomer Royal for Scotland' and a historical survey of the eight observatories that once populated Glasgow.