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Pharmacology of Neurotransmitter Release
It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.
Origins of Human Neuropathology: The Significance of Teneurin-Latrophilin Interaction
We are delighted to introduce this new special issue on “The Origins of Neuropathology: The Roles of Teneurins and Latrophilins”. Although the title may seem particularly bold, and indeed, perhaps presumptuous, we the editors, think our title well warranted based on the findings and interpretation provided by a dedicated group of researchers who have developed this field over the last 25 years. In this publication, we introduce the readers to researchers whom have pioneered this field, and those whom have played an essential role in developing this research direction. Now, together, their combined work have elucidated a novel ligandreceptor network that evolved during the earliest period...
Kinetics and Mechanisms of Chemical Reactions
Kinetics & Mechanisms of Chemical Reactions
The Hippocampus Book
Known to be important for memory, the hippocampus has long been a prime focus for neuroscience research. This second edition of The Hippocampus Book is written by experts in a wide range of disciplines, with new chapters summarizing how disorders of hippocampal function contribute to neurological and psychiatric conditions. The editors draw on their experience in hippocampal anatomy, physiology, cognitive neuroscience and disease pathobiology to weave together an authoritative book which will interest those working in numerous neuroscientific disciplines.
The Concept of Micellar-Sponge Nanophases in Chemical Physics of Polymers
The monograph is intended for elucidation of the novel trend in chemical physics regarding the polymer non-crystalline phase. It stresses the physical phenomena affecting the kinetics and mechanism of chemical reactions proceeding in the non-crystalline polymer matrix (NCPM). NCPM is depicted in terms of a supramolecular (carcass-micellar) model. T
Literary Journals in Imperial Russia
Given the restrictions on political action and even political discussion in Russia, Russian literary journals have served as the principal means by which Russia discovered, defined and shaped itself. Every issue of importance for literate Russians - social, economic, literary - made its appearance in one way or another on the pages of these journals, and virtually every major Russian novel of the nineteenth century was first published there in serial form. Literary Journals in Imperial Russia - a collection of essays by leading scholars, originally published in 1998 - was the first work to examine the extraordinary history of these journals in imperial Russia. The major social forces and issues that shaped literary journals during the period are analysed, detailed accounts are provided of individual journals and journalists, and descriptions are offered of the factors that contributed to their success.
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Adhesion‐GPCRs
Upon completion of the human genome project over 800 G protein-coupled receptor 1 (GPCR) genes, subdivided into five categories, were identified. These receptors sense a diverse array of stimuli, including peptides, ions, lipid analogues, light and odour, in a discriminating fashion. Subsequently, they transduce a signal from the ligand–receptor complex into numerous cellular responses. The importance of GPCRs is further reflected in the fact that they constitute the most common target for therapeutic drugs across a 2 wide range of human disorders. Phylogenetic analysis of GPCRs produced the GRAFS classification system, which subdivides GPCRs into five discrete families: glutamate, rhodops...
Handbook of Neurotoxicology
Neurotoxicology is a broad and burgeoning field of research. Its growth in recent years can be related, in part, to increased interest in and concern with the fact that a growing number of anthropogenic agents with neurotoxic potential, including pesticides, lead, mercury, and the polytypic bypro ducts of combustion and industrial production, continue to be spewed into and accumulate in the environment. In addition, there is great interest in natural products, including toxins, as sources of therapeutic agents. Indeed, it is well known that many natural toxins of broadly differing structure, produced or accumulated for predatory or defensive purposes, and toxic agents, accumulated incidental...
