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WHO consolidated guidelines on tuberculosis. Module 3
The "WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update" is the latest document replacing the one issued in 2020. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included in the latest consolidated guideline: 1. moderate complexity automated NAATs, recommended for the initial detection of TB and resistance to rifampicin and isoniazid, providing more options for early diagnosis of TB and rifampicin-resistant TB but also addressing an important gap in the rapid diagnosis of isoniazid-resistant and rifampicin-susceptible TB;2. low complexity automated NAATs, recommended for the detection of...
Good Participatory Practice
These Good Participatory Practice guidelines aim to provide systematic guidance on the roles and responsibilities of entities funding and conducting biomedical HIV prevention trials towards participants and their communities. Such entities include investigators, research staff, pharmaceutical industry sponsors, foundations, government-supported research networks, non-governmental research sponsors, and all others involved in designing, financing, and executing clinical trials research.
World TB Day 2023: Yes! We can end TB
World tuberculosis day takes place on the 24th of March, commemorating the date Robert Koch announced he had discovered TB bacillus, the bacterium causing tuberculosis. Tuberculosis is still a widespread epidemic in various parts of the world, leading to over one and a half million worldwide annual deaths, which disproportionally affects developing countries. The COVID-19 pandemic shifted countries’ focus away from tuberculosis, putting the goals of the End TB project at risk. The World Tuberculosis Day 2023 focuses on boosting awareness, hoping to increase public and political involvement —which will be crucial for the UN High-level meeting on TB in September 2023. Political will is nee...
WHO consolidated guidelines on tuberculosis. Module 3
The political declaration of the first United Nations (UN) high-level meeting on tuberculosis (TB) calls countries to diagnose and treat 40 million people with TB globally between 2018 and 2022. Traditionally, in most countries, TB diagnosis has been performed using sputum-smear microscopy, a method developed more than 100 years ago, with suboptimal sensitivity. In recent years new technologies have emerged based on the detection of mycobacterial DNA or mycobacterial antigens. Over the past decade the World Health Organization (WHO) has published a number of guidelines developed by WHO-convened Guideline Development Groups (GDGs), using the Grading of Recommendations Assessment, Development ...
