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Transgenic Xenopus
Annotation Explains techniques for microinjecting foreign genes into transgenic embryos of frogs and the information such research can provide about the role and spatiotemporal regulation of nervous system proteins during vertebrate development. Explains the basic scientific background and protocols, development, in vitro fertilization and microinjection, and a variety of biochemical and histochemical techniques for analyzing the results of the experiment. Also presents extensive data gathered by the approach. Annotation c. by Book News, Inc., Portland, Or.
Neurobiology of the Trace Amines
Many of the trace amines-more correctly called biogenic amines have been known for decades, but because of their tiny concentra tions (0. 01-100 ng/g) in brain, it was only after the development of sophisticated analytical techniques (such as mass spectrometry) that they could be identified and quantitated in nervous tissue. There are now more than 20 of them and most are related to the catecholamines and 5-hydroxytryptamine both structurally and metabolically. Their pharmacological and physiological properties make them prime candidates for a transmitter or neuromodulator role and many of them elicit profound behavioral syndromes after injection--one of them, phenylethylamine, has even been...
Trace Amines
This is the third Proceedings book to arise from biennial conferen ces on the Trace Amines. Since our first meeting in 1983 in Edmonton, Canada, progress has been brisk and, as will be seen from the ensuing pages, it is now possible to include major contributions from inverte brate neurobiologists as well as receptorologists. In the opening ses sion we heard about the distribution of the trace amines-now clear ly a misnomer-in insects and the pharmacological, receptor, and syn aptic characteristics of octopamine and tryptamine as well as the pos sibility of monoamines in general being targets for insecticide discov ery. In mammalian brain the distribution and characterization of the tryptami...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Amino Acids
Techniques in the neurosciences are evolving rapidly. There are currently very few volumes dedicated to the methodology - ployed by neurosclentlsts, and those that are available often seem either out of date or limited m scope. This series is about the methods most widely used by modern-day neurosclentists and 1s wrltten by their colleagues who are practicing experts. Volume 1 will be useful to all neurosclentists since It concerns those procedures used routinely across the widest range of subdisciplines. Collecting these general techniques together m a single volume strikes us not only as a service, but will no doubt prove of exceptIona utilitarian value as well. Volumes 2 and 3 - scribe al...
Animal Models in Psychiatry, I
The two Animal Models in Psychiatry volumes are loosely organized by subject. The first volume contains a number of chapters concerned with schizophrenia, psyc- ses, neuroleptic-induced tardive dyskinesias, and other d- orders that may involve dopamine, such as attention deficit disorder and mania. The second volume deals with affective and anxiety disorders, but also includes chapters on subjects not easily classified as either psychotic, or affective, or an- ety-related, such as aggression, mental retardation, and memory disorders. Four chapters on animal models of schizophrenia or psychoses are included in the present v- ume because of the importance of these disorders in p- chiatry. Like...
Variation in Chemical Composition of the Nervous System
Variation in Chemical Composition of the Nervous System: As Determined by Developmental and Genetic Factors documents the proceedings of the International Neurochemical Conference held in Oxford, 1965. The three years since the last neurochemical meeting have witnessed rapid progress in the whole field of biology, including the development of new concepts based on fresh experimental data and new technical tools. A great deal of concentrated effort have led to advances in the molecular aspects of biological processes ,which have perhaps had most to offer to the formation of new concepts of primary cellular events, especially the genetic mechanism, regulatory cell processes, and protein production. This volume contains 100 chapters that provide an overview of the state of knowledge on the genetic and developmental aspects of the central nervous system. Topics covered include the activity of a plasma logenase in the brain of the developing rat; genetic selection of rats differing in brain biochemistry; the effects of thyroid hormones on steroid deposition in developing chick brain; and developmental changes in the gamma globulins of bovine cerebrospinal fluid.
Patch-Clamp Analysis
Patch-Clamp Analysis: Advanced Techniques describes in reproducible detail all applications that involve patch pipet. Beginning with updated basic patch-clamp techniques, the book presents the newest developments, ranging from fast external solution switching and the switching of the pipet solution during recording, to the loose patch, the perforated patch, and the patch cram detection technique. The advanced techniques covered combine molecular biology and imaging to produce the patch pipet with RT-PCR and fluorometric techniques.
