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This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.
"Frontiers in CNS Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Central Nervous System (CNS) drug design and discovery. Eminent scientists write contributions on all areas of rational drug design an
The term “synaptic plasticity” is a broad concept, which is studied with a variety of experimental approaches. One focus is the impact of changes in synaptic, neuronal and glial morphology on brain circuitry and behavior. In this regard, unique animal models have been key to the study of affective and social behaviors and neurological and psychiatric diseases. However, there is a paucity of compilations directed toward the correlation of alterations in synaptic structure with various physiological and behavioral paradigms. This Frontiers Research Topic will, therefore, serve as an exciting forum for the exchange of novel hypotheses and data and an important resource and reference for investigators studying synaptic and brain plasticity, as well as those in related fields.
We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Neuroscience. Frontiers has organized a series of Research Topics to highlight the latest advancements in science in order to be at the forefront of science in different fields of research. This editorial initiative of particular relevance, led by Professors Jesper Sjöström, Karri P Lamsa, Alfredo Kirkwood, and supported by the Editorial Board of Frontiers in Synaptic Neuroscience is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of synaptic neuroscience.
In a step-by-step guide for healing inner-child wounds and overcoming codependency, certified integrative health coach Catherine Gerdes shares practical tools, in-depth reflections, and Ayurvedic wisdom that targets mindset healing and self-care practices while addressing the whole self to help others reconnect with their inner-strength, release stored away emotions, and arrive home to themselves. Throughout her manual, Gerdes reminds others that through conscious living and loving, we all have a chance to cocreate with the Divine while allowing ourselves to be guided from within. True Heart, Solid Boundaries shares tools, reflections, and Ayurvedic wisdom to lead others on a journey inward to heal and nurture their inner child, overcome codependency, and return home to their authentic truth.
There is no magic pill. There is no perfect diet. Could it be that our underlying assumption—that what we’re eating is making us fat and sick—is just plain wrong? To address the rapid rise of “lifestyle diseases” like diabetes and heart disease, scientists have conducted a whopping 500,000 studies of diet and another 300,000 of obesity. Journalists have written close to 250 million news articles combined about these topics. Yet nothing seems to halt the epidemic. Anastacia Marx de Salcedo’s Eat Like a Pig, Run Like a Horse looks not just to data-driven science, but to animals and the natural world around us for a new approach. What she finds will transform the national debate abo...