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The drama of Napoleon’s ill-fated invasion of Russia is captured through the letters and diaries of Polish soldiers who fought with the French. Napoleon’s invasion of Russia cost hundreds of thousands lives and changed the course of history. Europe had never seen an army like the one gathering in Poland in 1812—half a million men in brilliant uniforms and shimmering helmets. Six months later, it was the ghost of an army, frozen and horrified, retreating home. This illuminating volume tells the story of this epic military disaster from the viewpoint of the tens of thousands of Polish soldiers who took part. Some of them were patriots eager to regain independence for their country. Others were charmed by the glory of Napoleonic warfare or were professional soldiers who were simply doing their jobs. They all tell an unrivaled tale of ruthless battles, burning villages, numbing hunger, and biting cold. By the end the great army had been reduced to a pitiless mob and the Polish soldiers, who had set out with such hope, recalled it with horror.
¨The atherosclerotic process is considered to be driven by an imbalance between proand anti-inflammatory actions. Still, the inflammatory state in patients with coronary artery disease (CAD) remains to be clarified. Annexin A1 (AnxA1) is a glucocorticoidinduced protein which may have a key role in the anti-inflammatory response as a mediator of glucocorticoid effects. The general aim of this thesis was to deepen the knowledge of pro- and antiinflammatory mechanisms in CAD via phenotypic assessments of immune cell subsets, in particular CD56+ T cells, and exploration of AnxA1. The long-term goal is to reveal basic mechanisms that will lead to the development of biomarkers, which may be used ...
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The Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)
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Inflammation is closely associated with development of atherosclerosis. The proteolytic enzyme matrix metalloproteinase (MMP)-9 is considered to play a prominent role in this process. MMP-9 has also been introduced as a marker for plaque vulnerability. Still, the possible mechanisms behind altered levels of MMP-9 and its tissue inhibitors (TIMPs) in patients with atherosclerotic disease remain unclear. The general aim of this thesis was to compare leukocyte-derived MMP-9 and TIMPs in patients with coronary artery disease (CAD) and healthy controls and to further relate the findings to psychological stress and glucocorticoid sensitivity. Levels of leukocyte-derived MMP-9 and TIMP-1 showed a s...