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The book is the final report of the researches, discussions, conversations around and about the Project PRIN Employability & Competences which took place on March 9th-‐11th, 2017 within an International Conference at the University of Florence. It was the final event of the project PRIN2012LATR9N which aims were: «to design innovative programs for higher education, to promote personalized and learner-centered teaching and learning, to build on job competencies, to value talents to create new work opportunities, to support young adults during their employment emergency, as a response to socio economic crisis and as a citizenship action». The research activities concerned the main phases of the students’ academic life: career guidance upon entry, personalized teaching, career calling, professional vocation, profession building activities such as internships and work related experiences, and lastly job placement.
The beautiful young photojournalist, Aileen O’Shannon, is not who she seems. For centuries, she has been a demon hunter, a sorceress who has tracked and killed small bands of demons that occasionally crossed into our world. But that changed when she joined Dr. Jack Oswald’s expedition to study one of hundreds of huge holes that mysteriously appeared overnight in the frozen tundra north of the Arctic Circle. Instead of small sporadic incursions, hordes of demons now pour from these hell holes like water from a sieve. With bombing little more than a losing game of whack-a-mole, Earth’s armies are unable to destroy the portals. When Jack suggests a desperate plan, he is drafted to join Aileen and a team of other sorcerers and Army Rangers to travel to the demon homeworld. Once there, they will unleash a plague virus and set off a nuclear bomb to destroy the portal complex. It’s a suicide mission. But Aileen has given Jack’s wife her word to bring him back safely, and the demons have already killed three men under her protection. Just how far will Aileen go to avoid losing another?
Earning a doctorate can be a daunting, yet rewarding, venture; the doctoral journey can include immeasurable sacrifice (e.g., health, family, finances). This edited volume—a collective narrative—comprises diverse educationalist perspectives from scholars who have successfully navigated the doctoral journey. Clearly articulated throughout this collective narrative, there are innumerable ways to complete the doctoral journey; the laborious journey is not a linear process but rather a lattice of ever-evolving professional and personal relationships, experiences, perspectives, and insights. Personal accounts of resilience and growth serve as sources of inspiration while offering sage advice, genuine insights, and significant analyses—all seamlessly connected. Contributors are: Laurie Hill, Makie Kortjass, Michael Paul Lukie, Ntokozo Mkhize-Mthembu, David G. Ngatia, Heather Raymond, Alessandra Romano, Pearl Subban, Kathy Toogood and Barbara van Ingen.
Multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in bone marrow, leading to bone destruction and marrow failure. It accounts for approximately 1.8% of all hematologic and solid cancers and slightly > 15% of hematologic malignancies in the United States. MM is typically sensitive to different classes of cytotoxic drugs, both as frontline treatment and as treatment for relapsed disease. Unfortunately, even if responses are typically durable, nowadays MM is not considered curable with current approaches. However, MM survival rates have been brilliantly improved thanks to the introduction of novel agents: patients diagnosed after 2010 have had higher rates of novel therapy use and better survival outcomes compared with those of earlier years. Most relevant therapeutic advances over the past decades has been the introduction of novel therapies, such as immune-modifying agents (thalidomide and lenalidomide) and proteasome inhibitors (bortezomib), adopted with or without stem cell transplantation.
This handbook offers an expanded discourse on transformative learning by making the turn into new passageways to explore the phenomenon of transformation. It curates diverse discourses, knowledges and practices of transformation, in ways that both includes and departs from the adult learning mainstay of transformative learning and adult education. The purpose of this handbook is not to resolve or unify a theory of transformation and all the disciplinary contributions that clearly promote a living concept of transformation. Instead, the intent is to catalyze a more complex and deeper inquiry into the “Why of transformation.” Each discipline, culture, ethics and practice has its own specia...
This book provides qualitative analyses of intercultural sense making in a variety of institutional contexts. It relies on the assumption that in an increasingly culturally diverse world, individuals often enter contexts that have communal, historically determined and stable sets of values, norms and expected identities, with little cultural compass to find their bearings in them. The book goes beyond interpreting differences in people’s ethnic or linguistic roots and discusses instead people’s interpretive efforts to navigate different sociocultural situations. The contributors examine such situations in educational, organizational, medical and community settings and look at how participants with different levels of sociocultural competences (such as, migrant patients, migrant adult learners, children) try to cope with institutional constraints and expectations, how they understand symbols, practices and identities in institutional contexts, and how their creative adjustments come to light. This book provides insights from the fields of psychology, education, anthropology and linguistics, and is for a wide readership interested in cultural meaning-making.
Hematologic malignancies (HMs) represent a group of hematologic cancers originating from bone marrow or lymphoid organs. Currently, leukaemia, lymphoma, and multiple myeloma are the most common HMs. Conventional treatments for HMs include bone marrow transplantation, radiotherapy, chemotherapy, and immunotherapy. Despite the significant achievements obtained over the past decade in the drug therapy of HMs, tumor metastasis and relapse in patients often occurred after an initial response, indicating the generation of drug resistance to current therapies. Moreover, many clinically used therapeutic drugs are often associated with dose-related side effects and a lack of specificity to tumor tiss...
This book offers a concise and comprehensive exploration of the theory of transformative learning by European researchers. Exploring Mezirow’s theory of transformative learning as a ‘living theory’, the editors and contributors ask whether there a uniquely European perspective on this theory that reflects Europe’s traditions and contexts. What is the nature of that perspective, and how is it similar or different to those espoused in the USA? This book outlines how the theory of transformative learning has been developed by European researchers, and how it has built upon, critiqued, and enriched the Transformation Theory proposed by Mezirow. Consequently, this volume outlines new theoretical perspectives for the future evolution of transformative learning and explores theoretical perspectives that can be put into practice in a range of fields. This wide-ranging volume will be of interest and value to all those interested in transformative learning theory.
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults. The etiology of MS is not known, but it is generally accepted that it is autoimmune in nature. Our knowledge of the pathogenesis of MS has increased tremendously in the past decade through clinical studies and the use of experimental autoimmune encephalomyelitis (EAE), a model that has been widely used for MS research. Major advances in the field, such as understanding the roles of pathogenic Th17 cells, myeloid cells, and B cells in MS/EAE, as well as cytokine and chemokine signaling that controls neuroinflammation, have led to the development of potential and clinically approved disease-modifying agen...