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The Patient as a Person
In the current era, evidence-based medicine and various supporting technologies dominate everyday clinical practice, according to a disease-centred, as opposed to patient-centred, approach. They have obviously improved the clinical management of diseases and it is therefore unreasonable to think of a medicine in which they are not considered fundamental. In fact, the strength of the new medicine should be to adapt scientific knowledge to a specific clinical case. This book therefore looks at the prospect of a new 'person' centred medicine, which stands alongside the 'disease' and 'patient' centred medicine, which pays special attention to the subjectivity of scientific knowledge and the rela...
Thyroid and Heart Failure
Both thyroid dysfunction and heart failure show a high prevalence in the adult population. Frequently, in clinical practice, a multidisciplinary approach is useful to optimize the management of patients with these conditions. Although there is no doubt regarding the close link between cardiovascular pathophysiology and thyroid homeostasis, our understanding of this association is far from being exhaustive. Thyroid hormone regulates the expression of cardiac-specific functional contractile and structural proteins and plays a pivotal role in modulating both diastolic and systolic function as well as peripheral vascular resistance. The close relationship between thyroid and heart dysfunction is...
Adolescent Health and Wellbeing
This book presents a detailed and updated review of the widespread changes that take place during adolescence, adopting a preventive perspective that reflects physical, social, cognitive, and emotional changes. It addresses a broad range of aspects, including: the preventive programs and their systemic effects; the role of environment in influencing the healthy behaviors of adolescents and young adults; the use of e-Health technology in health and behavioral interventions for adolescents; and the clinical and prognostic implications of primordial prevention in healthy adolescents. All of these elements are subsequently reviewed using a multidimensional approach, in order to offer extensive i...
Thyroid and Heart
In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies – including multicenter studies – have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, struct...
MRI of the Heart and Vessels
In recent years magnetic resonance imaging (MRI) has enriched the technological potential available for the characterization of cardiovascular pathologies, adding substantial advantages to other non-invasive techniques. This technique, which is intrinsically digital and has reduced operator dependency, allows the performance of image analysis in a quantitative and reproducible manner. The use of non-ionizing energy with the consequent absence of an environmental impact and of operator and patient biohazards makes MRI a winning technique when evaluating the risk – benefit ratio in comparison to other imaging methods. In virtue of its added diagnostic value and inherent refinements that allow construction of two- and three-dimensional images, MRI is gaining a primary role in the histopathological and physiopathological understanding of a large number of pathologies concerning the heart and vessels. This text is addressed both to MRI operators seeking specific technical information and to clinicians who wish to have a better understanding of the diagnostic and management advantages that MRI can offer.
Frontiers in Cardiovascular Drug Discovery
"Frontiers in Cardiovascular Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Cardiovascular drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and d
Oxidative Stress in Heart Diseases
This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Sports cardiology
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