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First multi-year cumulation covers six years: 1965-70.
Multiple sclerosis is an unique disease with a tremendous impact on social life in countries with moderate climates. Its cause is unknown. In recent years however hopes have been raised that the disease might be fought, and possibly cured. With the disappearance of poliomyelitis as the main paralyzing disease multiple sclerosis has taken its place as the single disease that is responsible for paralyzing the young with an incurable affliction of long duration, for social disruption and for an 1 economic impact that is estimated to be higher than heart disease • A multi-national, mUlti-disciplinary approach to this extremely disabling disease is urgently needed in this phase of hopeful scientific developments. The Commission of the European Communities therefore sponsored a Con ference on Multiple Sclerosis Research in Europe on 29,30 and 31 January 1985 in Nijmegen, The Netherlands, with the aim of formulating practical proposals for such cooperation in the Communities. This volume contains the papers read at that conference.
Monoamine oxidase (MAO), a mitochondrial enzyme which metabolizes monoamines in both the central nervous system and peripheral tissues, plays an important role in the regulation of neuronal activities by controlling the concentrations of monoamines. During the past three decades the enzymological properties of MAO have been studied extensively. The most exciting and important advances in these studies have been the determination of the nucleotide sequence coding two forms of human MAO (MAO-A and MAO-B), and the involvement of MAO in potent dopaminergic neurotoxicity of MPTP, which had led to the acceleration of aetiological studies of Parkinson's disease. Other aspects of MAO studies have been the application of selective and safe MAO inhibitors in the treatment of depression and Parkinson's disease as well as the correlation between MAO and several psychiatric and neurodegenerative disorders.
The NATO Advanced Study Institute held in the Hotel Metropole Llandrindod Wells, Powys, Wales from July 26th to August 4th 1981 provided an excellent platform for presentation and appraisal of our current knowledge of neurotransmitter systems. The proceed ings comprise the present volume and these were arranged to allow study of the pathways and the interactions of specific transmitter systems, one with another, in the various sub-regions of the central nervous system. In addition several of the key factors involved in neurotransmitter release were highlighted. These include the structural and molecular organisation of the nerve terminal, its organelles (such as vesicles, neurotubules and sy...
For at least a half-century, there has been active debate on the nature of the economy between classical and neoclassical economists and advocates of a more -substantivist- approach (most recently, cultural anthropologists)... The essays are uniformly well written and excellently documented... Heartily recommended for academic libraries, community college level up. --S. M. Soiffer, Choice
Ch. 1. The brain as a survival machine -- ch. 2. A chemical code for survival -- ch. 3. Serotonin, steroids and signallung -- ch. 4. The brain and stress -- ch. 5. The weight-watcher in the brain -- ch. 6. Staying wet and salty -- ch. 7. Keeping warm, staying cool -- ch. 8. The sexual brain -- ch. 9. Bonding, motherhood and love -- ch. 10. The brain goes to war -- ch. 11. The ryhthm of life -- ch. 12. The brain breaks down -- ch. 13. Individuality.
Ambition, genius, thought, imagination, love, hate, greed and, above all, consciousness ourselves as alive and as part of our world — all this is somehow enabled by the brain. The brain is the person, and if it goes wrong, a person is ruined. This book is about part of what the brain does — a role of which many of us are hardly aware, but one that has ensured, the survival of mankind. Despite famine, drought, wars, cold, infections and hostile environments, we survive as a species — though not always as individuals. All this time, our brains have been coping with what fate throws at us — a process that some call adaptation. How does the brain do it? How does it know what's needed? Ho...