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Anti-idiotype antibodies in cancer treatment
Actively induced immunotherapy is one of the most promising fields in cancer research and numerous approaches are being studied to design effective cancer vaccines. Among the treatment strategies to develop an effective immune response against tumor associated antigens is the use of anti idiotype (Ab2) mAb as antigen surrogates. Several studies in animal models have demonstrated the efficacy of these vaccines for triggering the immune system to induce specific and protective immunity against tumors of different origin. In fact, anti-idiotypic mAbs have been used successfully in cancer therapeutics to overcome the poor immunogenicity of some tumor-associated antigens, in particular those of non-protein origin. In some clinical trials, including patients with different tumors, anti-Id specific humoral and/or cellular responses following immunization were associated with improved clinical outcome. This number of Frontiers will be dedicated to anti- idiotypic antibodies and their use in cancer treatment. Different article types will be considered: original contributions, case reports, methods, hypothesis and theory, reviews, historical, etc.
Blessed Pier Giorgio Frassati
Pier Giorgio Frassati lived only twenty-four short years, but lived them to the fullest. His student escapades, athletic achievements, and dedication to helping the poor combined to make this amazing young man a truly contemporary role model for young peo
Veracruz and the Caribbean in the Seventeenth Century
Explores how Veracruz's Afro-Mexican residents drew on Caribbean relationships to define a distinctive social and cultural community.
E-Business and Telecommunication Networks
This book contains the best papers of the Third International Conference on E-business and Telecommunications (ICETE), which was held in 2006 in Portugal. This conference reflects a continuing effort to increase the dissemination of recent research results among professionals who work in the e-business field. ICETE is a joint international conference integrating four major areas of knowledge that are divided into four cor- sponding conferences: ICE-B (Int’l Conf. on e-Business), SECRYPT (Int’l Conf. on Security and Cryptography), WINSYS (Int’l Conf. on Wireless Information Systems) and SIGMAP (Int’l Conf. on Signal Processing and Multimedia). The program of this joint conference incl...
New Trends in English Teacher Education
Here is a collection of papers exploring fron an interdisciplinary standpoint recent developments in teaching English as a second language. Insights into teaching methodologies, language adquisition adn applied linguistics encompass the use of literature and cultural studies in educational research, in order to provide teachers and scholars with a state-of-the-art account of the current progresses in foreing language education.
Recursos humanos en investigación y desarrollo. Universidades y CSIC
Recursos humanos en investigación y desarrollo.--V.2.
Love and the Law in Cervantes
The consolidation of law and the development of legal writing during Spain's Golden Age not only helped that country become a modern state but also affected its great literature. In this fascinating book, Roberto Gonzalez Echevarria explores the works of Cervantes, showing how his representations of love were inspired by examples of human deviance and desire culled from legal discourse.
Handbook of Autobiography / Autofiction
Autobiographical writings have been a major cultural genre from antiquity to the present time. General questions of the literary as, e.g., the relation between literature and reality, truth and fiction, the dependency of author, narrator, and figure, or issues of individual and cultural styles etc., can be studied preeminently in the autobiographical genre. Yet, the tradition of life-writing has, in the course of literary history, developed manifold types and forms. Especially in the globalized age, where the media and other technological / cultural factors contribute to a rapid transformation of lifestyles, autobiographical writing has maintained, even enhanced, its popularity and importanc...
