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This is the 5th volume in a WHO series on histological and genetic typing of human tumours. This edition focuses on cancers of the breast and female genital organs, and describes diagnostic criteria, pathological features, associated genetic alterations and gene expression patterns in a disease-oriented manner. Sections on all recognised neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics and predictive factors. It contains colour photographs, X-rays, computed tomography (CT) and magnetic resonance (MR) images, charts and over 3,200 references. The classifications presented reflect the views of WHO working group conferences held in France in January and March 2002, and the volume was produced in collaboration with the International Academy of Pathology.
Meeting the needs of haematologists, oncologists and clinical scientists for an up-to-date reference, this atlas provides a visual presentation of lymphoproliferative disorders, lymphoid leukaemias and plasma cell neoplasms. Each malignancy is surveyed based on molecular and cellular changes, including histochemistry, cytochemistry and relevant radiographs. Pertinent clinical information relating to clinical presentation, differential diagnosis and prognostic indicators are concisely outlined, using numerous graphics and citing key references in the field. CONTENTS: The molecular basis of lymphoma, Acute lymphoblastic leukaemia, Chronic lymphocytic leukaemia/small lymphocytic lymphoma and mo...
Peter Sinclair is a reasonably intelligent, fairly sociable, retired business executive, a family man attempting to carry on leading a full life, travelling and seeking safe adventures as befits his years. Family holidays should be pleasant, fun-filled times. Unfortunately, although he does not seek it, trouble seems to be attracted to Peter - not the what-a-pity sort of trouble you might expect of someone of his age and experience but serious trouble which might lead to his ultimate downfall. Crisis in Croatia sees him falling foul of a paramilitary group determined to achieve independence within Croatia; in Jewels of the Canaries he gets drawn into an attempt to smuggle stolen diamonds into Spain; in The Mysterious Case of the Disappearing Sea Salt he gets lost in a maze of smugglers' caves on the North Yorkshire coast; and, in Old Man of Hoy, he stumbles across an illicit Orkney whisky distillery with consequences far beyond his, and perhaps the reader's, expectations.
Major advances have occurred in the diagnosis and treatment of lymphoma in recent years. Our understanding of the molecular biology and genetics of the disease has increased exponentially, and significant imaging developments have resulted in earlier and more accurate diagnosis. The new edition of this landmark text places these advances in the context of daily clinical practice. Each chapter has been updated to reflect recent developments, including new treatment agents such as immunomodulatory drugs and the next generation of antibodies, and the increasing prognostic role of PET scanning. Results from recent large-scale clinical trials are presented, and pathology and cytogenetics are integrated into discussion of each disease entity, enabling the reader to review all the key diagnostic information in one place. Featuring many color illustrations, and written and edited by leading authorities in the field, Lymphoma provides all the information you need to diagnose and manage these complex disorders.
Reprint of the original, first published in 1842.
Highly Commended, BMA Medical Book Awards 2013Sarcoidosis represents a major challenge for physicians-not just in respiratory medicine, but across a range of specialties. This book, with a multidisciplinary authorship of the highest standard, presents the most up-to-date thinking on all aspects of the condition, from epidemiology to clinical manife
Lymphomas classically manifest themselves in the lymph nodes but can also present in other bodily tissues or systems; the organ where exactly they present may make a very great difference to the strategy that should be adopted for their management. This topic has only recently been consistently addressed as an issue on its own, apart from the rest