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A recently proposed novel scheme of dystonia suggests that it is a disorder of neural network. Impairment in any of the “nodes” of the network may result in deficient network activity, causing dystonia. This book aims to present various experimental evidence supporting the network theory of dystonia. Dystonia is the abnormal twisting and turning of the organ and associated involuntary oscillations. Although dystonia is less common than Parkinson’s disease, traumatic brain injury, or stroke, each of these common disorders present with dystonia. Information regarding the brain regions that may be involved in dystonia is surprisingly limited and often conflicting. With chapters written by subject matter experts, this is a unique title that focuses on dystonia as a network disorder. This book would be of interest to basic and clinical researchers with an interest in motor systems and movement disorders.
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This volume is a case-based guide to challenging clinical scenarios in neurology, covering 25 sub-speciality areas of the neurology curriculum. Each chapter is based around a potential real-life case, which is used as a platform to discuss the subject in a broader way and to explore the most up-to-date evidence regarding diagnosis and management.
Dystonia, Volume 169, the latest release in the International Review of Neurobiology serial, highlights new advances in the field with this new volume presenting interesting chapters on topics including Clinical Features and the Science of Classification, What Can Epidemiological Studies Tell us About the Neurobiology of Dystonia, Dystonia Genes and Their Biological Pathways, Functional Anatomy of Dystonia, Physiology of Dystonia: Human Studies, Physiology of Dystonia: Animal Studies, Experimental Pharmacology: Targeting Neurotransmitters, Experimental Pharmacology: Targeting Metabolic Pathways, Adult-Onset Focal Dystonias: One Biology or Many?, Early-Onset Inherited vs Late-Onset Idiopathic Dystonias: Same or Different Biological Mechanisms?, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in International Review on Neurobiology serials - Updated release includes the latest information on Dystonia
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic, Gaze Orienting Mechanisms and Disease, Volume 249, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Sequential Bayesian updating, Maps and Sensorimotor Transformations for Eye-Head Gaze Shifts: Role of the Midbrain Superior Colliculus, Modeling Gaze Position-Dependent Opsoclonus, Eye Position-Dependent Opsoclonus in Mild Traumatic Brain Injury, Saccades in Parkinson's disease -- hypometric, slow, and maladaptive, Brainstem Neural Circuits for Fixation and Generation of Saccadic Eye Movements, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Progress in Brain Research series - Includes the latest information on mathematical modeling in motor neuroscience
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This book is an attempt to advance the discussion and improve our understanding about the effects of aging and movement disorders on motor control during walking and postural tasks. Despite these activities are performed daily, there is a high requirement of motor and neural systems in order to perform both tasks efficiently. Both walking and posture require a complex interaction of musculoskeletal and neural systems. However, the mechanisms used to control these tasks, as well as how they are planned and coordinated, are still a question of discussion among health professionals and researchers. In addition, this discussion is more interesting when the effects of aging are included in the co...
This topic aims to pool the most recent advances in the phenomenology and pathophysiology of levodopa-induced dyskinesias. The papers in this eBook have strongly contributed to reduce the gaps in our knowledge of LIDs pathogenesis.