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NF-κB-Related Genetic Diseases
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.
In the Footsteps of Our Ancestors
In the Footsteps of Our Ancestors details through archaeological analysis, the dispersal of our species, Homo sapiens, providing a broad examination of evidence for early human migration into Asia and Oceania. Those migrations are crucial to our understanding of the global story of human evolution and cultural diversification. Chapters from an international team of experts provide the new geographical and temporal coverage. Controversies around timing, pathways, and competing models of migrations are explored in regions where archaeological data can be scarce. Genetic and archaeological data often seem inconsistent, but this book uses syntheses of archaeological evidence to give an updated view of our current knowledge of when and how these regions were first settled. These analyses help us understand the pattern of human movement and adaptation that led to the contemporary distribution of our species. This book provides the latest coverage of this important topic and contributes to thinking about the history of our species. In the Footsteps of Our Ancestors is an essential text for researchers and students of archaeology, anthropology, and human evolution.
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