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Smart Diagnostics for Neurodegenerative Disorders
Smart Diagnostics for Neurodegenerative Disorders: Neuro-sensors explores all available biosensor-based approaches and technologies as well as their use in the diagnosis, prognosis and therapeutic management of a variety of neurological disorders such as Alzheimer's, Parkinson's and epileptic disorders. The book also discusses contemporary and revolutionary biosensor platforms that are being used to produce a quantitative quick lab-on-a-chip point-of-care (POC) assay for several types of predictive and diagnostic biomarkers linked with neurodegenerative disorders. It offers a combinatorial strategy for learning recent advances and designing new biosensor-based technologies in the fields of m...
Performance Characterization of Lubricants
The text discusses the fundamentals of lubrication science and technology linking the science concepts to engineering practices. It further explores the performance characterization of lubrication systems by utilizing sophisticated experiments and tests and motivates the readers to develop their conclusions and reach solutions based on modern tools and techniques. This book: Presents the principles of surface and lubricant chemistry, and its implementation to devise engineering solutions for various application-based systems. Discusses viscosity index improvers, tribology of green lubricants, and biolubricants from non-edible oils. Highlights 2D nanomaterials lubricants, biogreases, hydrogel...
Hypoxia in Cancer: Significance and Impact on Cancer Therapy
This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.
Nanobiosensors for Environmental Monitoring
This book entails detailed information on the utilization of nanobiosensor as an effective technology for the effective detection, monitoring, and management of environmental contaminations to ensure its sustainability and humanity's well-being. The higher level of anthropogenic action has been identified as a threat to humankind's existence due to the higher level of xenobiotic and toxic substances that could interrupt the normal ecosystem. This has prompted numerous agencies both locally and internationally that could play a significant role in environmental pollution mitigation. The application of nanobiosensor has been identified as a sustainable technique that could be applied to ensure...
Industry 4.0 and Advanced Manufacturing
This book presents selected papers from the 2nd International Conference on Industry 4.0 and Advanced Manufacturing held at the Indian Institute of Science, Bangalore and includes deliberations from stakeholders in manufacturing and Industry 4.0 on the nature, needs, challenges, opportunities, problems, and solutions in these transformational areas. Special emphasis is placed on exploring avenues for creating a vision of, and enablers for, sustainable, affordable, and human-centric Industry 4.0. The book showcases cutting edge practice, research, and educational innovation in this crucial and rapidly evolving area. This book will be useful to researchers in academia and industry, and will also be useful to policymakers involved in creating ecosystems for implementation of Industry 4.0.
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications...
Remediation of Heavy Metals
Meet the challenge of contaminated soil with a range of sustainable tools The remediation of soils which have been polluted by trace metals is an increasingly significant environmental challenge in an industrialized global economy. The ongoing revolution in green technologies, however, has seen a range of sustainable methods emerge for remediating soils, water, and other aspects of the environment polluted by trace metals. By putting them into practice, environmental researchers and industrial professionals will be able to improve soil and groundwater quality and public health globally. Remediation of Heavy Metals offers a clear, accessible reference on these methods and their applications. ...
Lab-on-a-chip Devices for Advanced Biomedicines
The global miniature devices market is poised to surpass a valuation of $12–$15 billion USD by the year 2030. Lab-on-a-chip (LOC) devices are a vital component of this market. Comprising a network of microchannels, electrical circuits, sensors, and electrodes, LOC is a miniaturized integrated device platform used to streamline day-to-day laboratory functions, run cost-effective clinical analyses and curb the need for centralized instrumentation facilities in remote areas. Compact design, portability, ease of operation, low sample volume, short reaction time, and parallel investigation stand as the pivotal factors driving the widespread acceptance of LOC within the biomedical community. In ...
