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Recent Advances in Oral Immunity
The oral mucosa is a challenging environment from an immunological perspective, containing discrete niches with a unique architecture and function that requires precise adjustment of the immune system. Being the port of entry to the gastrointestinal and respiratory tracts, the oral cavity is also constantly challenged by antigens derived from air and food. Moreover, the oral cavity is the sole tissue of the body harboring a hard surface (i.e. the tooth) that is exposed to the hostile external environment, resulting in the formation of a complex biofilm that has local and systemic effects. To deal with such challenges, the oral immune system aims to prevent the invasion of pathogens/harmful antigens and to tolerate non-pathogenic counterparts in order to maintain homeostasis. In recent years, numerous studies have addressed these fundamental issues, revealing sophisticated mechanisms engaged by the immune system to maintain oral mucosal homeostasis and to combat various immunological insults. Some of these studies have identified novel immunological mechanisms, emphasizing the uniqueness of the oral immune system and the necessity to further investigate its functions.
Oral Mucosal Immunity and Microbiome
The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.
Project Renewal in Israel
Although it is too early for a final evaluation of this internationally important urban revitalization program, which channelled one billion dollars into 84 distressed neighborhoods throughout Israel, Project Renewal has undoubtedly improved the social, welfare, educational and physical condition of hundreds of thousands of Israelis as well as improving the image of many neighborhoods. Co-published with the Center for Jewish Community Studies/Jerusalem Center for Public Affairs.
Inflammation
This volume presents a broad selection of cutting-edge methods and tools that will enable the reader to investigate the multi-faceted manifestations of inflammation. Inflammation: Methods and Protocols is divided into four sections: the first three sections describe protocols investigating immune-mediated inflammatory disease models affecting barrier organs to the environment; the skin, the lung, and the intestinal and oral mucosa. The fourth section illustrates inflammatory disease models of the brain, joints, and vasculature. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and practical, Inflammation: Methods and Protocols aims to inspire the experienced investigator and the young experimenter alike to disentangle the fascinating process of inflammation.
Trabajo social y servicios sociales
Este manual persigue como finalidad convertirse en el instrumento necesario para la formación de los trabajadores sociales en una perspectiva internacional. Como es habitual en nuestra Universidad (UNED) las asignaturas se apoyan en textos básicos que comprenden sus contenidos y por este propósito se ha realizado esta publicación, con el fin explícito de aunar los análisis de diferentes autores sobre el origen, desarrollo y evolución del Trabajo Social en sus respectivos países. Gracias a la colaboración de la Asociación Internacional de Escuelas de Trabajo Social y la Asociación Europea, cuyos presidentes participan además en este texto por medio de sus respectivos capítulos, h...
Human Fungal Pathogen Identification
This detailed volume presents timely and authoritative content offering a comprehensive overview of the current state of the art in fungal diagnostics. Moreover, it addresses on-going developments expected to provide a basis for targeted treatment strategies resulting in improved outcome of invasive mycoses. The knowledge of host-related predisposing factors and stratified treatment options facilitating timely onset of adequate antifungal therapy are critical for successful clinical management and outcome of invasive fungal disease (IFD), requiring not only rapid diagnosis of a fungal infection and identification of the causative species, but also assessment of pathogen/host factors related ...
The Tiberian Pronunciation Tradition of Biblical Hebrew, Volume 1
These volumes represent the highest level of scholarship on what is arguably the most important tradition of Biblical Hebrew. Written by the leading scholar of the Tiberian Masoretic tradition, they offer a wealth of new data and revised analysis, and constitute a considerable advance on existing published scholarship. It should stand alongside Israel Yeivin’s ‘The Tiberian Masorah’ as an essential handbook for scholars of Biblical Hebrew, and will remain an indispensable reference work for decades to come. —Dr. Benjamin Outhwaite, Director of the Taylor-Schechter Genizah Research Unit, Cambridge University Library The form of Biblical Hebrew that is presented in printed editions, wi...
Statistics for Linguists
Linguists with no background in statistics will find this book to be an accessible introduction to statistics. Concepts are explained in non-technical terms, and mathematical formulas are kept to a minimum. The book incorporates SPSS, which is a statistics package that incorporates a point and click interface rather than complex line-commands. Step-by-step instructions are provided for some of the most widely used statistics in linguistics. At the same time, the concepts behind each procedure are also explained. Traditional analyses such as ANOVA and t-tests are included in the book, but linguistic data is often not amenable to such analyses. For this reason, non-parametric and mixed-effects procedures are also introduced.
