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Boundaries between Promotion and Progression during Carcinogenesis
The pUrpOSE! of this conference was not to define the two areas that are being bound, which might be a well nigh impossible proposition. Rather, its focus was to concentrate on the mechanistic similarities between promotion and progression. Are the areas involved within the boundaries a continuum? Are these two simultaneous processes? Or are some of the affected cells in the stage of promotion when at the same time others have undergone irreversi ble changes tha. t position them in the stage of progression? Or are these two stages the same thing, but called by different names? To explore such concepts we assembled investigators with various back grounds and asked them to specifically address...
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy
For this Workshop, the organizers have attempted to invite experts from all known centers which are engaged in neutron beam development for neutron capture therapy. The Workshop was designed around a series of nineteen invited papers which dealt with neutron source design and development and beam characterization and performance. Emphasis was placed on epithermal beams because they offer clinical advantages and are more challenging to implement than thermal beams. Fission reactor sources were the basis for the majority of the papers; however three papers dealt with accelerator neutron sources. An additional three invited papers provided a summary of clinical results of Ncr therapy in Japan b...
Synchrotron Radiation in Structural Biology
The development of synchrotron radiation (SR) as a research tool was driven largely by the needs of materials scientists and solid-state physi cists. However, the availability of SR has extended significantly the capa bility of scientists who study biological structure with radiation. This volume contains some of the results reported at a symposium held at Brookhaven National Laboratory in May 1988 to discuss the application of synchrotron radiation to structural biology. We are grateful for financial support from the u. s. Department of Energy, the National Institutes of Health, Genentech, Inc., Blake Indus tries, Inc., Evans and Sutherland Co., The Upjohn Company, Eli Lilly and Company, En...
In Vivo Body Composition Studies
This book is the compilation of papers presented at the International Symposium on in vivo Body Composition Studies, held at the University of Toronto, Ontario, Canada, June 20 - 23, 1989. The purpose of this conference was to report on advances in techniques for the in vivo measurement of body composition and to present recent data on normal body composition and changes during disease. This conference was the most recent of several meetings on body composition studies, and follows two successful such meetings, one at Brookhaven National Laboratory in 1986, and at Edinburgh in 1988. The large number of excellent research papers and posters presented at these conferences demonstrates the rapi...
NMR Applications in Biopolymers
Elucidating the structures of biopolymers as they exist in nature has long been a goal of biochemists and biologists. Understanding how these substances interact with themselves, other solutes, and solvents can provide useful insights into many areas of biochemistry, agriculture, food science and medicine. Knowledge of the structure of a protein or complex carbohydrate in its native form provides guidelines for the chemical or genetic modifications often desired to optimize these compounds to specific needs and applications. For example, in the pharmaceutical industry, structure-function relationships involving biopolymers are studied rou tinely as a means to design new drugs and improve the...
Human Body Composition
This book is the compilation of papers presented at the International Symposium on In Vivo Body Composition Studies, held in Houston, Texas, November 10-12, 1992. The purpose of this conference was to report on the state-of-the-art techniques for in vivo body composition measurements and to present the most recent human data on normal body composition and changes during disease. This conference was the third in a series of meetings on body composition studies held in North America, and follows the successful meetings at Brookhaven National Laboratory in 1986, and the one in Toronto in 1989. A large number of excellent research papers were offered for consideration at this Conference which de...
Biology of Adventitious Root Formation
Charles E. Hess Department of Environmental Horticulture University of California Davis, CA 95616 Research in the biology of adventitious root formation has a special place in science. It provides an excellent forum in which to pursue fundamental research on the regulation of plant growth and development. At the same time the results of the research have been quickly applied by commercial plant propagators, agronomists, foresters and horticulturists (see the chapter by Kovar and Kuchenbuch, by Ritchie, and by Davies and coworkers in this volume). In an era when there is great interest in speeding technology transfer, the experiences gained in research in adventitious root formation may provi...
Biology of Root Formation and Development
This book contains the majority of the presentations of the Second International Symposium on the Biology of Root Formation and Development that was hcld in Jerusa lem, Israel, June 23---28, 1996. Following the First Symposium on the Biology of Adventi tious Root Formation, held in Dallas. USA, 1993, we perceived the need to include all kinds of roots, not only the shoot-borne ones. The endogenous signals that control root formation. and the subsequent growth and development processes, are very much alike, re gardless of the sites and sources of origin of the roots. Therefore, we included in the Sec ond Symposium contributions on both shoot-borne (i.e., adventitious) roots and root-borne (i....
Clinical Aspects of Neutron Capture Therapy
Since Locher first suggested Boron Neutron Capture Therapy (BNCT) in 1936, this theoretically ideal system has intrigued investigators. Unfortunately, the first clinical trials between 1951-1961 were not successful. However, they served to implant firmly the seed of BNCT, the growth of which has been carefully nurtured at a number of locations world-wide. This fact is attested to by the ongoing clinical trials in Japan as well as by the presence of researchers from active groups in the ten countries represented at this Workshop. In 1983 and 1985, the first and second international biannual symposia on BNCT were held, in response to a resurgence of interest in this field. In 1986, the DOE spo...
Plant Polyphenols
This book was developed from the proceedings of the 2nd North American Tan nin Conference held in Houghton, Michigan, June, 1991. The objective of this con ference was to bring together people with a common interest in plant polyphenols and to promote interdisciplinary interactions that will lead to a bet ter understand ing of the importance of these substances. Another objective of this conference was to extend the 'tannin family' by making special efforts to encourage participation by scientists outside the United States, obtain more coverage of the hydrolyzable tannins, and further broaden the scope of coverage from the initial concentration on forestry and forest products. Com parison of...
